Evidence map›Paper›PMID 39131130›Full record

ReviewGastro hep advances2022

Global Prevalence, Risk Factors, and Outcomes of Depression After Liver Transplant: A Systematic Review and Meta-analysis.

Wen Hui Lim, Chen Wei Poh, Beatrice Jia Min Tan, Cheng Han Ng, Darren Jun Hao Tan, Xiong Chang Lim, Phoebe Wen Lin Tay, Grace En Hui Lim, Daniel Q Huang, Cyrus S H Ho and 7 more

Abstract readReview
In one paragraph

Review in Gastro hep advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Wen Hui LimYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chen Wei PohYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Beatrice Jia Min TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Cheng Han NgYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Darren Jun Hao TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Xiong Chang LimYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Phoebe Wen Lin TayYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Grace En Hui LimYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Daniel Q HuangYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Cyrus S H HoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Eunice Xiang-Xuan TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nicholas SynYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yock Young DanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Konstadina GrivaCentre for Population Health Sciences, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
James FungDepartment of Surgery, Division of Liver Transplantation, Queen Mary Hospital, Hong Kong.
Mohammad Shadab SiddiquiDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia.
Mark Dhinesh MuthiahYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: With existing literature focusing on general quality of life, the magnitude and impact of depression among recipients after liver transplantation (LT) is unclear. Hence, we aim to evaluate the prevalence, risk factors, and outcomes for recipient-related depression after LT. Methods: Medline and Embase were searched. Single-arm analysis was pooled using the generalized linear mixed model, and logistic regression was performed to analyze risk factors. Pairwise comparative meta-analysis in odds ratio was conducted for binary outcomes. Results: Of 1069 abstracts, 189 articles underwent full-text review before the inclusion of 48 articles. Pooled depression rate among 5170 recipients was 24.52% (confidence interval [CI]: 19.46%-30.41%). Depression was most prevalent in Asia compared with other geographical regions. Younger age at transplantation ( Conclusion: Depression is highly prevalent after LT and may be associated with increased mortality and poorer graft outcomes. More emphasis is needed on the screening of depression among higher risk recipients.

Indexed as

Liver TransplantationMental HealthMood DisordersPsychological Wellbeing

Identifiers

PMID39131130
PMCPMC11307655

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.