Evidence map›Paper›PMID 39131008›Full record

ArticleCureus2024

Anti-CASPR2 Antibody-Associated Autoimmune Encephalitis Presenting as Refractory Seizures.

Nivedha Balaji, Aleksandra Ignatowicz, Aarushi Kalra, Rami Mansour, Vaishali Jadhav

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nivedha BalajiInternal Medicine, Northeast Georgia Medical Center Gainsville, Gainesville, USA.
Aleksandra IgnatowiczInternal Medicine, Northeast Georgia Medical Center Gainsville, Gainesville, USA.
Aarushi KalraInternal Medicine, Northeast Georgia Medical Center Gainsville, Gainesville, USA.
Rami MansourInternal Medicine, Philadelphia College of Osteopathic Medicine, Suwanee, USA.
Vaishali JadhavInternal Medicine, Northeast Georgia Medical Center Gainsville, Gainesville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune encephalitis (AE) is a rare immune-mediated disorder comprised of non-infectious neuroinflammatory disease processes. Clinical presentation overlaps with a broad range of neurodegenerative disorders and infectious encephalitis; therefore, AE remains a diagnosis of exclusion. Patients may present with nonspecific symptoms such as psychiatric disturbances, cognitive deficits, seizures, movement disorders, and confusion. Prompt diagnosis and management are necessary for patients with AE to decrease mortality and improve quality of life. First-line therapy includes immunosuppression with corticosteroids, intravenous immunoglobulin, and plasmapheresis. We report the case of an 86-year-old female with a medical history of Parkinson's disease who presented with nonspecific seizure-like activity and was diagnosed with AE.

Indexed as

autoimmune encephalitisencephalitidesencephalitisparaneoplastic syndromerecurrent seizures

Identifiers

PMID39131008
PMCPMC11316415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.