Evidence map›Paper›PMID 39130709›Full record

ReviewJournal of the Society for Cardiovascular Angiography & Interventions

Antiplatelet Strategies Following PCI: A Review of Trials Informing Current and Future Therapies.

Alexander Thomas, Mauro Gitto, Samit Shah, Yuichi Saito, Daniela Tirziu, Alaide Chieffo, Giulio G Stefanini, Alexandra J Lansky

Abstract readReview
In one paragraph

Review in Journal of the Society for Cardiovascular Angiography & Interventions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Efficacy and safety of dual anti-platelet aggregation short post-pharmacologic stent].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Pooled it
  2. Ticagrelor monotherapy versus ticagrelor plus aspirin in patients with chronic coronary syndrome and high ischaemic risk: a post hoc analysis of the TWILIGHT trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Trial
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Observational
  8. Article
  9. Review
  10. Paclitaxel-coated balloon with urea or iopromide as the excipient for treatment of coronary artery disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  11. Article
  12. Medical Management of Coronary Artery Disease: An Update.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander ThomasSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Mauro GittoSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Samit ShahSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Yuichi SaitoSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Daniela TirziuSection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.
Alaide ChieffoInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Giulio G StefaniniDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, Italy.
Alexandra J LanskySection of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.

Funding

FDA HHS U01 FD005938
6 · The paper itself

Abstract

Dual antiplatelet therapy (DAPT) has been paramount in preventing thrombosis following percutaneous coronary intervention for nearly 3 decades. However, over the years, DAPT has seen significant changes in the agents utilized and duration of therapy as trials have raced to keep up with advancements made in stent technology and our understanding of bleeding and ischemic risk. Recently, there have been a number of trials demonstrating significant reductions in bleeding events with shorter DAPT durations, which are not yet reflected in practice guidelines. Further, there has been a shift toward more individualized antiplatelet regimens to meet patient-specific risk profiles. This review provides a comprehensive summary of the major trials that have informed current DAPT strategies, puts into context recent trials driving a shift toward more tailored antiplatelet regimens, and highlights gaps in knowledge that remain and the ongoing trials designed to address them.

Indexed as

dual antiplatelet therapypercutaneous coronary interventionpharmacotherapy

Identifiers

PMID39130709
PMCPMC11307978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.