Evidence map›Paper›PMID 39130370›Full record

ArticleAdvanced materials technologies2023

Intervertebral Disc-on-a-Chip

Wanqing Xie, Yuan Xing, Li Xiao, Pu Zhang, Richard Oh, Yangpu Zhang, Xiaoyu Yu, Yi He, Eunha G Oh, Ruofan Cao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials technologies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wanqing XieDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Yuan XingDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Li XiaoDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Pu ZhangDepartment of Mechanical and Aerospace Engineering, University of Virginia, 122 Engineer's Way, Charlottesville, VA 22904, USA.
Richard OhDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Yangpu ZhangDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Xiaoyu YuDepartment of Surgery, University of Virginia, 345 Cripell Drive, Charlottesville, VA 22908, USA.
Yi HeDepartment of Surgery, University of Virginia, 345 Cripell Drive, Charlottesville, VA 22908, USA.
Eunha G OhDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Ruofan CaoDepartment of BioMolecular Science, University of Mississippi, Oxford, MS 38677, USA.
Melur K RamasubramanianDepartment of Mechanical and Aerospace Engineering, University of Virginia, 122 Engineer's Way, Charlottesville, VA 22904, USA.
Yong WangDepartment of Visceral Surgery and Transplantation, University of Zurich Hospital, 8091 Zürich, Switzerland.
Li JinDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.
Jose OberhozlerDepartment of Visceral Surgery and Transplantation, University of Zurich Hospital, 8091 Zürich, Switzerland.
Xudong LiDepartment of Orthopaedic Surgery, University of Virginia, Charlottesville, VA 22908, USA.

Funding

Deciphering Macrophage Phenotype and Function in Disc Herniation and associated Back/leg PainR01AR078888 · NIAMS · UNIVERSITY OF VIRGINIA · PI XUDONG J. LI · 2022 to 2026
$1.8M
An Integrated Fluorescent Biosensor, Imaging, and Analysis Toolkit for Islet BiologicsR01DK122253 · NIDDK · UNIVERSITY OF VIRGINIA · PI AI, HUIWANG · 2020 to 2023
$1.6M
Systemic Application for Injury Site Specific Delivery via Neutrophils to Treat BR01AR064792 · NIAMS · UNIVERSITY OF VIRGINIA · PI LI, XUDONG J. · 2013 to 2018
$1.3M
Disc-on-a-chip: microfluidic nutrition and biomechanical loading integrated mouse disc culture systemR21AR072334 · NIAMS · UNIVERSITY OF VIRGINIA · PI LI, XUDONG J. · 2018 to 2019
$391k
An ex vivo system to model the inflammatory microenvironment of human disc herniationR21AR078547 · NIAMS · UNIVERSITY OF VIRGINIA · PI LI, XUDONG J., POMPANO, REBECCA R · 2021 to 2021
$388k
Macrophage Anchoring Nanomedicine to Replace Steroids for Intra-articular InjectionR21AR082052 · NIAMS · UNIVERSITY OF VIRGINIA · PI JIN, LI, LI, XUDONG J. · 2023 to 2024
$384k
NIAMS NIH HHS R01 AR064792NIAMS NIH HHS R01 AR078888NIAMS NIH HHS R21 AR072334NIAMS NIH HHS R21 AR078547NIAMS NIH HHS R21 AR082052NIDDK NIH HHS R01 DK122253
6 · The paper itself

Abstract

This study aims to develop an

Indexed as

bioreactorintervertebral disc degenerationmechanical loadingmicrofluidicorgan-on-a-chip

Identifiers

PMID39130370
PMCPMC11315454

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.