Dimeric Drug Polymeric Micelles with Acid-Active Tumor Targeting and FRET-indicated Drug Release.

Xing Guo, Lin Wang, Kayla Duval, Jing Fan, Shaobing Zhou, Zi Chen

Abstract readPreprint

In one paragraph

Article in ArXiv, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xing GuoThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

Lin WangThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

Kayla DuvalThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

Jing FanThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

Shaobing ZhouKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Chengdu 610031, China.

Zi ChenThayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

Funding

Epithelial layer jamming in breast cancer cell migrationU01CA202123 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J · 2015 to 2019

$3.4M

NCI NIH HHS U01 CA202123

6 · The paper itself

Abstract

Trans-activating transcriptional activator (TAT), a cell-penetrating peptide, has been extensively used for facilitating cellular uptake and nuclear targeting of drug delivery systems. However, the positively charged TAT peptide usually strongly interacts with serum components and undergoes substantial phagocytosis by the reticuloendothelial system, causing a short blood circulation

Identifiers

PMID39130205

PMCPMC11312624

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.