Evidence map›Paper›PMID 39130083›Full record

ArticleOpen forum infectious diseases2024

Estimating and Explaining the Differences in Health Care Seeking by Symptom Burden Among Persons With Presumptive Tuberculosis: Findings From a Population-Based Tuberculosis Prevalence Survey in a High-Burden Setting in India.

Prathiksha Giridharan, Karikalan Nagarajan, Sriram Selvaraju, Asha Frederick, Esakkipriya Subbiah, Sasikumar Mani, Kannan Thiruvengadam, T S Selvavinayagam, Chandrasekaran Padmapriyadarsini, Tamil Nadu TB Prevalence Study Group

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Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Prathiksha GiridharanICMR-National Institute for Research in Tuberculosis, Chennai, India.
Karikalan NagarajanICMR-National Institute for Research in Tuberculosis, Chennai, India.ORCID https://orcid.org/0000-0001-7462-7066
Sriram SelvarajuICMR-National Institute for Research in Tuberculosis, Chennai, India.
Asha FrederickDirectorate of Medical and Rural Health Services & State TB Cell, Chennai, India.
Esakkipriya SubbiahICMR-National Institute for Research in Tuberculosis, Chennai, India.
Sasikumar ManiICMR-National Institute for Research in Tuberculosis, Chennai, India.
Kannan ThiruvengadamICMR-Regional Medical Research Centre, Port Blair, Andaman and Nicobar Islands.
T S SelvavinayagamDirectorate of Public Health and Preventive Medicine, Chennai, India.
Chandrasekaran PadmapriyadarsiniICMR-National Institute for Research in Tuberculosis, Chennai, India.ORCID https://orcid.org/0000-0002-1324-4595
Tamil Nadu TB Prevalence Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is a lack of research evidence on the quantitative relationship between symptom burden and health care seeking among individuals with presumptive tuberculosis (TB). Methods: Data were derived from a cross-sectional population-based TB survey conducted between February 2021 and July 2022 in 32 districts of India. Eligible and consented participants (age >15 years) underwent TB symptom screening and history elicitation. Fairlie decomposition analysis was used to estimate the net differences in health care seeking due to varied symptom burden-from 1+ burden (>1 symptom) to 4+ burden (>4 symptoms)-and decomposed by observable covariates based on logit models with 95% CIs. Results: Of the 130 932 individuals surveyed, 9540 (7.3%) reported at least 1 recent TB symptom, of whom 2678 (28.1%; 95% CI, 27.1%-28.9%) reportedly sought health care. The net differences in health care seeking among persons with symptom burden 1+ to 4+ ranged from 6.6 percentage points (95% CI, 4.8-8.4) to 7.7 (95% CI, 5.2-10.2) as compared with persons with less symptom burden. The presence of expectoration, fatigue, and loss of appetite largely explained health care seeking (range, 0.9-3.1 percentage points [42.89%-151.9%]). The presence of fever, cough, past TB care seeking, weight loss, and chest pain moderately explained (range, 5.3%-25.3%) health care seeking. Conclusions: Increased symptom burden and symptoms other than the commonly emphasized cough and fever largely explained health care seeking. Orienting TB awareness and risk communications toward symptom burden and illness perceptions could help address population gaps in health care seeking for TB.

Indexed as

decompositionhealth seekingIndiasymptomstuberculosis

Identifiers

PMID39130083
PMCPMC11310591

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