Evidence map›Paper›PMID 39129910›Full record

ArticleInternational journal of microbiology2024

Antimicrobial and Antibiofilm Activity of Monolaurin against Methicillin-Resistant

Shimaa Salah Hassan Abd El-Ghany, Ahmed Farag Azmy, Ahmed Osama El-Gendy, Rehab Mahmoud Abd El-Baky, Ahmad Mustafa, Mohammed A S Abourehab, Mohamed E El-Beeh, Reham Ali Ibrahem

Abstract read
In one paragraph

Article in International journal of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shimaa Salah Hassan Abd El-GhanyDepartment of Microbiology and Immunology Faculty of Pharmacy Beni-Suef University, Beni-Suef 62514, Egypt.ORCID https://orcid.org/0009-0007-3382-956X
Ahmed Farag AzmyDepartment of Microbiology and Immunology Faculty of Pharmacy Beni-Suef University, Beni-Suef 62514, Egypt.ORCID https://orcid.org/0000-0002-7347-9564
Ahmed Osama El-GendyDepartment of Microbiology and Immunology Faculty of Pharmacy Beni-Suef University, Beni-Suef 62514, Egypt.ORCID https://orcid.org/0000-0002-0980-5185
Rehab Mahmoud Abd El-BakyDepartment of Microbiology and Immunology Faculty of Pharmacy Deraya University, Minia 11566, Egypt.ORCID https://orcid.org/0000-0001-6094-5653
Ahmad MustafaFaculty of Engineering October University for Modern Science and Arts (MSA), Giza, Egypt.ORCID https://orcid.org/0000-0001-7254-5665
Mohammed A S AbourehabDepartment of Pharmaceutics Faculty of Pharmacy Minia University, Minia 61519, Egypt.
Mohamed E El-BeehBiology Department Al-Jumum University College Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Reham Ali IbrahemDepartment of Microbiology and Immunology Faculty of Pharmacy Minia University, Minia 61519, Egypt.ORCID https://orcid.org/0000-0002-3249-4290

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methicillin-resistant Methods: The agar dilution method determined the minimum inhibitory concentration (MIC) of monolaurin against MRSA isolates and explored its impact on the resistance profile of selected antibiotics. The assessment of combined therapy involving monolaurin and antibiotics was conducted using fractional inhibitory concentration (FIC). The tissue culture plate strategy appraised monolaurin's antibiofilm activity and its inhibitory concentration (IC Results: Monolaurin exhibited MIC values ranging from 500 to 2000 Conclusion: Monolaurin had significant inhibitory effects on MRSA pre-existing biofilms as well as biofilm development. So, it can be employed in the treatment of severe infections, particularly those associated with biofilm formation including catheter-associated infections.

Identifiers

PMID39129910
PMCPMC11315973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.