Evidence map›Paper›PMID 39129819›Full record

ArticleJCEM case reports2024

Rapid Resolution of Recalcitrant Headache With Pasireotide in an Adult Patient With Acromegaly.

Zeinab Dabbous, Zaina Rohani, Abeer Kaled Abdalrubb, Yaman Alkailani, Rosario Pivonello, Tarik Elhadd

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zeinab DabbousEndocrine Section, Department of Medicine, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.ORCID https://orcid.org/0000-0001-7022-3806
Zaina RohaniEndocrine Section, Department of Medicine, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Abeer Kaled AbdalrubbEndocrine Section, Department of Medicine, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Yaman AlkailaniRadiology Department, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Rosario PivonelloDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, 80131 Naples, Italy.ORCID https://orcid.org/0000-0002-9632-1348
Tarik ElhaddEndocrine Section, Department of Medicine, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is a chronic hormonal disorder caused by excessive GH secretion. In addition to physiological symptoms, it is often accompanied by debilitating headaches. Although effective treatment options exist, achieving complete symptom control and disease management can still be challenging. This case report chronicles the clinical journey of a 38-year-old male diagnosed with acromegaly in 2013. Despite prior interventions, including surgery and treatment with first-generation somatostatin analogues, severe frequent headaches persisted. Following a switch to pasireotide, the patient reported rapid and complete resolution of headaches and normalization of IGF-1 levels within a month of the treatment switch. This report underscores the challenges in acromegaly management and confirms the potential utility of pasireotide for patients suffering from treatment-resistant headache.

Indexed as

acromegalyheadachepasireotide

Identifiers

PMID39129819
PMCPMC11311708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.