ArticleJournal of the Society for Cardiovascular Angiography & Interventions
Safety and Effectiveness of Mechanical Thrombectomy From the Fully Enrolled Multicenter, Prospective CLOUT Registry.
Article in Journal of the Society for Cardiovascular Angiography & Interventions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ClotTriever Outcomes (CLOUT) Registry
Prospective, Multicenter, Registry of the FLOWRUNNER Aspiration System for Safety and Effectiveness in the Removal of Symptomatic Venous Thrombosis (FAST)
Who cites it
23 citing papers in PubMed.
- Comparison of anticoagulation vs mechanical thrombectomy for the treatment of iliofemoral deep vein thrombosis.Journal of vascular surgery. Venous and lymphatic disorders · 2024Trial
- Mechanical thrombectomy and venous-dedicated stent implantation for acute iliofemoral deep vein thrombosis with iliac vein compression.Journal of cardiology cases · 2026Article
- A 10-year review of iliofemoral deep vein thrombosis - are they more dangerous than their distal counterparts?Journal of thrombosis and thrombolysis · 2026Article
- Carbon dioxide Venography-Guided ClotTriever thrombectomy for Deep Vein Thrombosis.Cardiovascular intervention and therapeutics · 2026Article
- Evidence for Mechanical Thrombectomy in Iliofemoral Deep Vein Thrombosis Remains Consistent.Cardiovascular and interventional radiology · 2025Article
- Prevention of the Postthrombotic Syndrome: Where Do We Stand?Seminars in interventional radiology · 2025Review
- Review
- Percutaneous aortoiliac thromboendarterectomy with Inari ClotTriever system for chronic juxtarenal aortoiliac occlusion.Journal of vascular surgery cases and innovative techniques · 2025Article
- Venous microtrauma associated with pharmacomechanical catheter-directed thrombolysis in a large animal acute deep venous thrombosis model.Frontiers in cardiovascular medicine · 2025Article
- Iatrogenic arteriovenous fistula after endovenous mechanical thrombectomy.Journal of vascular surgery cases and innovative techniques · 2024Article
- Current Evidence for Endovascular Therapies in the Management of Acute Deep Vein Thrombosis.Cardiovascular and interventional radiology · 2024Review
- Mechanical thrombectomy for inferior vena cava tumor thrombus secondary to renal cell carcinoma.Journal of vascular surgery cases and innovative techniques · 2024Article
- DETECT-DVT: Detroit Evaluation of Thrombectomy and Evaluation of Intravascular Ultrasound in Deep Vein Thrombosis.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Initial experience with the ambulatory management of acute iliofemoral deep vein thrombosis with May-Thurner syndrome with percutaneous mechanical thrombectomy, angioplasty and stenting.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Outcomes From Mechanical Thrombectomy for Deep Vein Thrombosis: Insights From the PINC AI Healthcare Database.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Treating hemodialysis access thrombosis with the InThrill Thrombectomy System: Technique and case report.Radiology case reports · 2024Article
- Management of Iliofemoral Venous Stent Thrombosis.Seminars in interventional radiology · 2024Review
- One-Year Clinical Outcomes Following Mechanical Thrombectomy for Deep Vein Thrombosis: A CLOUT Registry Analysis.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Mechanical thrombectomy of venous in-stent thrombosis with the novel RevCore thrombectomy system: A report of 2 cases.Radiology case reports · 2024Article
- Endovascular interventions in cancer patients with compromise of the mediastinal vasculature: a review.Mediastinum (Hong Kong, China) · 2024Review
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We report in-hospital outcomes from the multicenter, prospective, single-arm ClotTriever Outcomes (CLOUT) registry, which enrolled up to 500 patients with proximal lower extremity deep vein thrombosis (DVT) treated with percutaneous mechanical thrombectomy using the ClotTriever System (Inari Medical). Methods: The CLOUT registry enrolled all-comer patients with DVT, irrespective of symptom duration, thrombus age, prior treatment of the current DVT, or bilateral thrombus. The primary effectiveness end point was defined as complete or near complete (≥75%) reduction in Marder score. Thrombus burden was assessed by an independent core laboratory. Mortality and serious adverse events, including device-relatedness, were adjudicated by an independent medical monitor. Here, safety and outcomes are evaluated through discharge. Results: The median age was 61.9 years (IQR, 48.0-70.8), 50.5% were women, 24.9% had a history of DVT, and 23.2% had previously failed treatment of the current DVT. Nearly all procedures (99.4%) were performed in a single session with negligible procedural blood loss (median 40.0 mL; IQR, 20.0-50.0), and most patients (97.8%) required no subsequent intensive care unit monitoring. The primary effectiveness end point was achieved in 91.2% of limbs. Through discharge, 1 device-related serious adverse event (0.2%) occurred. Health status, as assessed by self-reported pain and circumferential measurements of limb edema, were significantly improved at discharge. Conclusions: Thrombectomy with the ClotTriever System is a safe and effective treatment for proximal lower extremity DVT, while also avoiding the need of intensive care. Early patient improvements are demonstrated, and follow-up is ongoing to 2 years.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.