Evidence map›Paper›PMID 39129157›Full record

ReviewCurrent pediatric reviews2025

Clinical Picture, Diagnosis, Management of NEC, and Effects of Probiotics on its Prevention: A Narrative Review.

Giuseppe De Bernardo, Carla Ziello, Grazia Parisi, Carolina Vecchione, Valentina Fattorusso, Simona Spadarella, Maurizio Giordano, Giuseppe Buonocore, Serafina Perrone

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pediatric reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giuseppe De BernardoDepartment of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy.
Carla ZielloDivision of Pediatrics, Department of Transaltional Medical Sciences, University of Naples Federico II, Naples, Italy.
Grazia ParisiDivision of Pediatrics, Department of Transaltional Medical Sciences, University of Naples Federico II, Naples, Italy.
Carolina VecchioneDivision of Pediatrics, Department of Transaltional Medical Sciences, University of Naples Federico II, Naples, Italy.
Valentina FattorussoDepartment of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy.
Simona SpadarellaDepartment of Woman and Child, Buon Consiglio Fatebenefratelli Hospital, Naples, Italy.
Maurizio GiordanoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Giuseppe BuonocoreDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Serafina PerroneNeonatology Unit, Department of Medicine and Surgery, University of Parma, Pietro Barilla Children's Hospital, Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm newborns represent a population at risk of developing intestinal dysbiosis as well as being predisposed to sepsis and Necrotizing Enterocolitis. Necrotizing Enterocolitis is a condition burdened by many complications and mortality due to an alteration of the intestinal barrier, an immaturity of the immune system, and intestinal dysbiosis. Low gestational age at birth, low birth weight, and early use of antibiotics are other predisposing factors. Instead, breast milk and probiotics are protective factors in providing intestinal homeostasis and microbiome regulation. In this mini-review, we analysed the protective role of probiotics in the onset of Necrotizing Enterocolitis in preterm populations.

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesProbioticsDysbiosisGastrointestinal MicrobiomeHumansInfant, NewbornInfant, PrematureMilk, Humandysbiosislow body weightmetabolites.mothernecrotizing enterocolitisPreterm newbornsprobiotics

Identifiers

PMID39129157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.