ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2024
The Effects of Gluten on Weight Gain, Hematological, Biochemical, and Various Endocrinological Parameters.
Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- A Randomized Controlled Trial Comparing Low-FODMAP and Gluten-Free Diets on Gastrointestinal Symptoms, Nutritional Status, and Quality of Life in Irritable Bowel Syndrome.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Systemic Immune-Inflammation Index and Selected Immune-Based Scores in the Diagnosis and Monitoring of Celiac Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- Non-Celiac Wheat Gluten Sensitivity Model: Effects on Hepatic Morphophysiology of Wistar Rats.Nutrients · 2025Article
- Can the Mucosa Heal Histologically in Celiac Disease? What are the Indicators of Remission in Celiac Patients?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Non-celiac Gluten Sensitivity: A New Clinical Entity or Growing Controversy?Euroasian journal of hepato-gastroenterologyReview
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThis study is aimed to compare the effects of nutrition which has been enriched with different amounts of gluten to gluten-free diets on weight gain, diabetogenic state, hematological, and biochemical parameters. MATERIALS AND
methodsA total of 40 newly weaned male Wistar albino rats used in the study were randomized into 4 different groups based on the gluten rations they were given. Following 12 weeks of diet they were killed and intracardiac blood samples were collected. Groups were identified as group 1 (n = 10): control group; normal rat ration containing wheat, group 2 (n = 10): gluten-free diet, group 3 (n = 10): ration containing medium level of gluten (normal rat diet+6% vital gluten) and group 4 (n = 10): ration containing high level of gluten (normal rat diet+12% vital gluten).
resultsIn groups 3 and 4, high-density lipoprotein was found to be higher than the other 2groups. However, when group 2 results were compared to the other groups; the highest T3, T4, creatinine and B12 levels and the lowest gluten-specific IgE level were observed. alanine aminotransferase and aspartate aminotransferase levels were found to be higher in group 1 compared to the other 3 groups. No statistically significant difference was detected between the groups in terms of other parameters.
conclusionThis study provides evidence that a gluten-containing diet does not cause weight gain, has no diabetogenic effect, and also does not adversely affect general health in relation to hematological, biochemical, and various endocrinological parameters.
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