Evidence map›Paper›PMID 39127896›Full record

SynthesisAnnals of Saudi medicine

Efficacy and safety of autologous platelet-rich plasma in anal fistula: a systematic review and meta-analysis.

Yuanhui Xu, Lin Ma, Keliang Jia, Xiaoling Wu, Chang Ge

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuanhui XuFrom the Department of Anus and Intestine Surgery, Anorectal Surgery, The First Affiliated Hospital of Shandong, First Medical University, Shandong, China.
Lin MaFrom the Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Shandong, First Medical University, Shandong, China.
Keliang JiaFrom the Department of Anus and Intestine Surgery, Anorectal Surgery, The First Affiliated Hospital of Shandong, First Medical University, Shandong, China.
Xiaoling WuFrom the Department of Anus and Intestine Surgery, Laiwu Vocational and Technical College, Shandong, China.
Chang GeFrom the Department of Anus and Intestine Surgery, Jinan Central Hospital Affiliated to Shandong University, Shandong, China.ORCID 0009-0005-7987-840X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to determine the efficacy and safety of autologous PRP in anal fistula.

methodsThe search was done in electronic databases such as; PubMed, Scopus, Google Scholar, Embase, and Cochrane Library. The outcomes investigated in this study were the rate of improvement, the rate of recurrence, and the rate of fecal incontinence.

resultsCure, incontinence, and recurrence rates were 68% (95% CI, .60-.76), 27% (95% CI, .12-.46), and 18% (95% CI, .12-.26), respectively. The pooled improvement ratio in patients treated with PRP compared to control group was 1.35 times, which was statistically significant (pooled OR=1.35, 95% CI, 1.14-1.60, DISCUSSION: Platelet-rich plasma is an effective method of healing people with anal fistula.

Indexed as

Fecal IncontinencePlatelet-Rich PlasmaRectal FistulaRecurrenceHumansTreatment Outcome

Identifiers

PMID39127896
PMCPMC11316947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.