Evidence map›Paper›PMID 39127799›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Delayed facial nerve palsy after vestibular schwannoma resection: risk factors, extent and prognosis.

Miriam Simon, Laurenz Althaus, Manuel Burggraf, Angelika Albrecht, Jörg Schipper, Julia Kristin

Abstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Miriam SimonDepartment of Otorhinolaryngology, University Hospital Düesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany. Miriam.Simon@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0002-5116-8888
Laurenz AlthausDepartment of Otorhinolaryngology, University Hospital Düesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Manuel BurggrafDepartment of Trauma surgery and Orthopedics, Essen University Hospital, Hufelandstraße 55, 45147, Essen, Germany.
Angelika AlbrechtDepartment of Otorhinolaryngology, University Hospital Düesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Jörg SchipperDepartment of Otorhinolaryngology, University Hospital Düesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Julia KristinDepartment of Otorhinolaryngology, University Hospital Düesseldorf Head and Neck Surgery, Moorenstrasse 5, 40225, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFacial nerve palsies may develop during the postoperative period of microsurgical removal of vestibular schwannomas (VSs), even after normal facial function for days or weeks after surgery. The aim of this study was to identify the pathomechanism and predictive factors of delayed palsy. MATERIAL AND

methodThe clinical data of 193 patients who underwent vestibular schwannoma surgery between 2012 and 2021 were retrospectively analyzed. A total of 134 patients were included. The patients showed intact facial nerve function up to 24 h after surgery. All patients (n = 20) with palsy from postoperative day 4 were included and collectively referred to as delayed facial nerve palsy (DFNP). Various factors were checked using a binomial regression analysis.

resultsThe mean age of patients with DFNP was 57.8 years (55% female, 45% male). 70% had VS with KOOS ≥ 3, and 60% underwent surgery via a translabyrinthine approach Among the 16 patients with DFNP-related neurotropic pathogens, 25% were seropositive for herpes simplex virus. Most patients (n = 9/20) experienced onset of palsy between postoperative days 6 and 10. Of the four variables included in the significance test, three were significant: KOOS ≥ 3 (p < .04), ipsilateral vestibular organ failure (p < .05), and age group (p < .03). After therapy, 100% of patients recovered almost complete facial nerve function. The parameters mentioned above (KOOS classification and ipsilateral vestibular dysfunction) could be proven risk factors for the occurrence of DFNP.

Indexed as

Facial ParalysisNeuroma, AcousticPostoperative ComplicationsAdultAgedFemaleHumansMaleMicrosurgeryMiddle AgedPrognosisRetrospective StudiesRisk FactorsTime FactorsCranial nerve failureDelayed facial nerve palsyFacial nerve outcomesSkull base surgeryVestibular schwannoma

Identifiers

PMID39127799
PMCPMC11564273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.