Evidence map›Paper›PMID 39127666›Full record

ArticleBMC microbiology2024

Multi-omics analysis reveals genes and metabolites involved in Streptococcus suis biofilm formation.

Haikun Wang, Qingying Fan, Yuxin Wang, Li Yi, Yang Wang

Abstract read
In one paragraph

Article in BMC microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Metabolomics study of the inhibitory effects of tubuloside A on Streptococcus suis biofilm.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haikun Wang *College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, China.
Qingying Fan *College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, China.
Yuxin WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, China.
Li YiHenan Provincial Engineering Research Center for Detection and Prevention and Control of Emerging Infectious Diseases in Livestock and Poultry, Luoyang, 471003, China.
Yang WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, 471000, China. wangyocean@163.com.

Funding

Excellent Youth Foundation of He'nan Scientific Committee 222300420005Henan Provincial Science and Technology Research Project 232102110095Key Scientific Research Projects of Universities in Henan Province (24A230013)Program for Innovative Research Team (in Science and Technology) in University of Henan Province 24IRTSTHN033the National Natural Science Foundation of China 32172852
6 · The paper itself

Abstract

backgroundStreptococcus suis is an important zoonotic pathogen. Biofilm formation largely explains the difficulty in preventing and controlling S. suis. However, little is known about the molecular mechanism of S. suis biofilm formation.

resultsIn this study, transcriptomic and metabolomic analyses of S. suis in biofilm and planktonic states were performed to identify key genes and metabolites involved in biofilm formation. A total of 789 differential genes and 365 differential metabolites were identified. By integrating transcriptomics and metabolomics, five main metabolic pathways were identified, including amino acid pathway, nucleotide metabolism pathway, carbon metabolism pathway, vitamin and cofactor metabolism pathway, and aminoacyl-tRNA biosynthesis metabolic pathway.

conclusionsThese results provide new insights for exploring the molecular mechanism of S. suis biofilm formation.

Indexed as

BiofilmsStreptococcus suisBacterial ProteinsGene Expression ProfilingGene Expression Regulation, BacterialMetabolic Networks and PathwaysMetabolomeMetabolomicsMultiomicsTranscriptomeBacterial ProteinsBiofilmMetabolomicsMulti-omics analysisStreptococcus suisTranscriptomics

Identifiers

PMID39127666
PMCPMC11316374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.