Evidence map›Paper›PMID 39127663›Full record

ArticleBMC veterinary research2024

Whole-genome sequencing of multidrug-resistant Klebsiella pneumoniae with capsular serotype K2 isolates from mink in China.

Na Sun, Yong Yang, Guisheng Wang, Li Guo, Liming Liu, Zhihao San, Cuiqing Zhao, Lifeng Zhao, Mingwei Tong, Yuening Cheng and 1 more

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In one paragraph

Article in BMC veterinary research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Drug resistance and pathogenicity characteristics ofFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Na Sun *College of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Yong Yang *School of Basic Medical Sciences, Shanxi Medical University, Taiyuan, China.
Guisheng WangShandong Provincial Center for Animal Disease Control and Prevention, Jinan, China.
Li GuoCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Liming LiuCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Zhihao SanCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Cuiqing ZhaoCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Lifeng ZhaoCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China.
Mingwei TongSchool of Basic Medical Sciences, Shanxi Medical University, Taiyuan, China.
Yuening ChengKey Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Institute of Special Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, China.
Qiang ChenCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin, China. chenqiangdoctor17@163.com.

Funding

Doctoral Foundation of Jilin Agricultural Science and Technology University 20217014Jilin Province Science and Technology Development Plan Project Assignment 20200201108JCJilin Province Science and Technology Research Project of Education Department JJKH20220401KJ
6 · The paper itself

Abstract

backgroundKlebsiella pneumoniae is a zoonotic opportunistic pathogen, and also one of the common pathogenic bacteria causing mink pneumonia. The aim of this study was to get a better understanding of the whole-genome of multi-drug resistant Klebsiella pneumoniae with K2 serotype in China. This study for the first time to analyze Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment, resistance and virulence genes of Klebsiella pneumoniae in mink.

resultsThe isolate was Klebsiella pneumoniae with serotype K2 and ST6189 by PCR method. The string test was positive and showed high mucus phenotype. There was one plasmid with IncFIB replicons in the genome. The virulence factors including capsule, lipopolysaccharide, adhesin, iron uptake system, urease, secretory system, regulatory gene (rcsA, rcsB), determinants of pili adhesion, enolase and magnesium ion absorption related genes. The strain was multi-drug resistant. A total of 26  resistance genes, including beta-lactam, aminoglycosides, tetracycline, fluoroquinolones, sulfonamides, amide alcohols, macrolides, rifampicin, fosfomycin, vancomycin, diaminopyrimidines and polymyxin. Multidrug-resistant efflux protein AcrA, AcrB, TolC, were predicted in the strain.

conclusionIt was the first to identify that serotype K2 K. pneumonia with ST6189 isolated from mink in China. The finding indicated that hypervirulent and multi-drug resistant K. pneumoniae was exist in Chinese mink. The whole-genome of K. pneumoniae isolates have importance in mink farming practice.

Indexed as

Drug Resistance, Multiple, BacterialKlebsiella pneumoniaeMinkSerogroupWhole Genome SequencingAnimalsAnti-Bacterial AgentsChinaGenome, BacterialKlebsiella InfectionsVirulence FactorsAnti-Bacterial AgentsVirulence FactorsK2 serotypeKlebsiella pneumoniaeMinkResistance genesVirulence genes

Identifiers

PMID39127663
PMCPMC11316373

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