Evidence map›Paper›PMID 39127035›Full record

ArticleMed (New York, N.Y.)2024

Storage, preservation, and rehabilitation of living heart valves to treat congenital heart disease.

Elizabeth M Cordoves, Giovanni Ferrari, Emmanuel Zorn, Emile Bacha, Gordana Vunjak-Novakovic, David M Kalfa

Abstract read
In one paragraph

Article in Med (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth M CordovesVagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Biomedical Engineering, Columbia University, New York, NY, USA.
Giovanni FerrariDepartment of Biomedical Engineering, Columbia University, New York, NY, USA; Department of Surgery, Columbia University, New York, NY, USA.
Emmanuel ZornColumbia Center for Translational Immunology, Columbia University Medical Center, New York, NY, USA.
Emile BachaDivision of Cardiac, Thoracic, and Vascular Surgery, Section of Pediatric and Congenital Cardiac Surgery, New York-Presbyterian Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, USA.
Gordana Vunjak-NovakovicDepartment of Biomedical Engineering, Columbia University, New York, NY, USA; Department of Medicine, Columbia University, New York, NY, USA. Electronic address: gv2131@columbia.edu.
David M KalfaDivision of Cardiac, Thoracic, and Vascular Surgery, Section of Pediatric and Congenital Cardiac Surgery, New York-Presbyterian Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, USA. Electronic address: dk2757@cumc.columbia.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007367 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI REINER, STEVEN L · 1985 to 2021
$25.1M
Tissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6M
An expandable polymeric valved conduit to repair congenital heart diseaseR01HL155381 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FERRARI, GIOVANNI · 2021 to 2025
$2.8M
Revision to Mechanisms of accelerated calcification and structural degeneration of implantable biomaterials in pediatric cardiac surgeryR01HL163085 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Giovanni Ferrari · 2023 to 2026
$2.7M
NHLBI NIH HHS R01 HL155381NHLBI NIH HHS R01 HL163085NIBIB NIH HHS P41 EB027062NIGMS NIH HHS T32 GM007367
6 · The paper itself

Abstract

Heart valve disease patients undergo multiple surgeries to replace structurally degraded valve prostheses, highlighting the need for valve replacements with growth and self-repair capacity. Given allogeneic valve transplantation's promise in meeting these goals by delivering a living valve replacement, we propose a framework for preserving and rehabilitating living valves ex vivo.

Indexed as

Heart Defects, CongenitalHeart Valve ProsthesisHeart Valve DiseasesHeart Valve Prosthesis ImplantationHeart ValvesHumans

Identifiers

PMID39127035
PMCPMC11807255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.