Evidence map›Paper›PMID 39126488›Full record

Observational studyDiabetologia2024

Accuracy of continuous glucose monitoring in the hospital setting: an observational study.

Mollie Y O'Connor, Kristen L Flint, Amy Sabean, Annabelle Ashley, Hui Zheng, Joyce Yan, Barbara A Steiner, Nillani Anandakugan, Melissa Calverley, Rachel Bartholomew and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Understanding Glycemia in the Post Discharge Period Through Blinded Continuous Glucose Monitoring.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Observational
  6. Article
  7. Inpatient Diet Orders and Continuous Glucose Monitoring in Noncritically Ill, Hospitalized Adult Patients.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Observational
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mollie Y O'Connor *Diabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0769-1396
Kristen L Flint *Diabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6941-9385
Amy SabeanDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Annabelle AshleyDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Hui ZhengBiostatics Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6725-1910
Joyce YanBiostatics Center, Massachusetts General Hospital, Boston, MA, USA.
Barbara A SteinerDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Nillani AnandakuganDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Melissa CalverleyDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Rachel BartholomewDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8418-6495
Evelyn GreauxDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Mary LarkinDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.
Steven J RussellDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8423-5891
Melissa S PutmanDiabetes Research Center, Massachusetts General Hospital, Boston, MA, USA. msputman@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-7655-8954

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
Clinical studies of a bionic pancreas for automated glucose management in cystic fibrosis-related diabetes mellitusR01DK119699 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI PUTMAN, MELISSA SUSAN · 2019 to 2024
$3.4M
Dexcom Investigator-Initiated Studies grantDivision of Diabetes, Endocrinology, and Metabolic Diseases R01DK119699-S1Division of Diabetes, Endocrinology, and Metabolic Diseases T32DK007028NIDDK NIH HHS R01 DK119699NIDDK NIH HHS T32 DK007028
6 · The paper itself

Abstract

aims/hypothesisContinuous glucose monitoring (CGM) improves glycaemic outcomes in the outpatient setting; however, there are limited data regarding CGM accuracy in hospital.

methodsWe conducted a prospective, observational study comparing CGM data from blinded Dexcom G6 Pro sensors with reference point of care and laboratory glucose measurements during participants' hospitalisations. Key accuracy metrics included the proportion of CGM values within ±20% of reference glucose values >5.6 mmol/l or within ±1.1 mmol/l of reference glucose values ≤5.6 mmol/l (%20/20), the mean and median absolute relative difference between CGM and reference value (MARD and median ARD, respectively) and Clarke error grid analysis (CEGA). A retrospective calibration scheme was used to determine whether calibration improved sensor accuracy. Multivariable regression models and subgroup analyses were used to determine the impact of clinical characteristics on accuracy assessments.

resultsA total of 326 adults hospitalised on 19 medical or surgical non-intensive care hospital floors were enrolled, providing 6648 matched glucose pairs. The %20/20 was 59.5%, the MARD was 19.2% and the median ARD was 16.8%. CEGA showed that 98.2% of values were in zone A (clinically accurate) and zone B (benign). Subgroups with lower accuracy metrics included those with severe anaemia, renal dysfunction and oedema. Application of a once-daily morning calibration schedule improved accuracy (MARD 11.4%). CONCLUSIONS/

interpretationThe CGM accuracy when used in hospital may be lower than that reported in the outpatient setting, but this may be improved with appropriate patient selection and daily calibration. Further research is needed to understand the role of CGM in inpatient settings.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringAdultAgedCalibrationContinuous Glucose MonitoringFemaleHospitalizationHospitalsHumansMaleMiddle AgedProspective StudiesBlood GlucoseAccuracyCalibrationContinuous glucose monitoringHospitalInpatient

Identifiers

PMID39126488
PMCPMC12509055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.