Evidence map›Paper›PMID 39126438›Full record

ArticleAnnals of surgical oncology2024

Peritoneal Dissemination in Patients with Recurrence After Post-pleurectomy/decortication for Pleural Mesothelioma.

Akifumi Nakamura, Masaki Hashimoto, Ayumi Kuroda, Kyoshiro Takegahara, Akihiro Fukuda, Seiji Matsumoto, Nobuyuki Kondo, Toshiyuki Minami, Kazuhiro Kitajima, Kozo Kuribayashi and 3 more

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Article in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Akifumi NakamuraDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan. xxmp97511@zeus.eonet.ne.jp.ORCID http://orcid.org/0000-0001-5742-9527
Masaki HashimotoDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Ayumi KurodaDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Kyoshiro TakegaharaDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Akihiro FukudaDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Seiji MatsumotoDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Nobuyuki KondoDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Toshiyuki MinamiDivision of Respiratory Medicine and Hematology, Department of Internal Medicine, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Kazuhiro KitajimaDepartment of Radiology, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Kozo KuribayashiDivision of Respiratory Medicine and Hematology, Department of Internal Medicine, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Takashi KijimaDivision of Respiratory Medicine and Hematology, Department of Internal Medicine, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Soichiro FunakiDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Seiki HasegawaDivision of Thoracic Surgery, Department of Surgery, Hyogo Medical University, Nishinomiya, Hyogo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn clinical practice, peritoneal dissemination after curative-intent surgery for pleural mesothelioma occasionally recurs. This study investigated the risk factors and prognosis associated with post-pleurectomy/decortication peritoneal dissemination in pleural mesothelioma, which are rarely reported.

methodsThis retrospective review included 160 patients who experienced recurrence after pleurectomy/decortication for pleural mesothelioma between January 2011 and December 2021. Patients with recurrence were classified according to the initial recurrence pattern. The P group experienced recurrence with peritoneal dissemination, and the non-P group experienced recurrence without peritoneal dissemination. The analysis determined the risk factors for peritoneal dissemination using multivariable logistic regression analysis. Survival was analyzed using the Kaplan-Meier method and the log-rank test.

resultsOf the 160 patients, 20 (12.5%) exhibited peritoneal dissemination and were assigned to the P group, whereas 140 (87.5%) had recurrence without peritoneal dissemination and were assigned to the non-P group. Multivariable logistic regression analysis showed that diaphragm reconstruction (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.0-8.0; p = 0.048) and female sex (OR, 3.7; 95% CI 1.26-10.8; p = 0.017) were associated with the P group. Post-recurrence survival was worse in the P group than in the non-P group (1-year post-recurrence survival: 22.2% vs. 65.3%; median: 6.7 months vs. 19.4 months; p = 0.0013).

conclusionsPeritoneal dissemination occurred in approximately one of every eight patients with recurrence after pleurectomy/decortication for pleural mesothelioma, and the incidence was significantly higher among females and patients undergoing diaphragm reconstruction. Moreover, postoperative recurrence of peritoneal dissemination was associated with a poor prognosis.

Indexed as

MesotheliomaNeoplasm Recurrence, LocalPeritoneal NeoplasmsPleural NeoplasmsAgedFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMesothelioma, MalignantMiddle AgedPleuraPrognosisRetrospective StudiesRisk FactorsDiaphragm reconstructionPleural disseminationPleural mesotheliomaPleurectomy/decorticationRecurrence

Identifiers

PMID39126438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.