Evidence map›Paper›PMID 39126310›Full record

ReviewLeukemia & lymphoma2024

Prospects for liquid biopsy approaches in lymphomas.

Esraa Jamal, Edward Poynton, Mohamed Elbogdady, Sameh Shamaa, Jessica Okosun

Abstract readReview
In one paragraph

Review in Leukemia & lymphoma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. [Analysis of clinical characteristics and delays in diagnosis of the lymphoma of sinonasal cavities].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  3. Review
  4. Article
  5. Liquid Biopsy in B and T Cell Lymphomas: From Bench to Bedside.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esraa JamalCentre of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
Edward PoyntonCentre of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
Mohamed ElbogdadyClinical Haematology Unit, Oncology Center, Mansoura University, Mansoura, Egypt.
Sameh ShamaaClinical Haematology Unit, Oncology Center, Mansoura University, Mansoura, Egypt.
Jessica OkosunCentre of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.ORCID 0000-0001-6021-5044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Analytes within liquid biopsies have emerged as promising alternatives to traditional tissue biopsies for various malignancies, including lymphomas. This review explores the clinical applications of one such liquid biopsy analyte, circulating tumor DNA (ctDNA) in different types of lymphoma, focusing on its role in diagnosis, disease monitoring, and relapse detection. Advancements in next-generation sequencing (NGS) and machine learning have enhanced ctDNA analysis, offering a multi-omic approach to understanding tumor genetics. In lymphoma, ctDNA provides insights into tumor heterogeneity, aids in genetic profiling, and predicts treatment response. Recent studies demonstrate the prognostic value of ctDNA and its potential to improve patient outcomes by facilitating early disease detection and personalized treatment strategies Despite these advancements, challenges remain in optimizing sample collection, processing, assay sensitivity, and overall consensus workflows in order to facilitate integration into routine clinical practice.

Indexed as

Biomarkers, TumorCirculating Tumor DNALymphomaHigh-Throughput Nucleotide SequencingHumansLiquid BiopsyPrognosisBiomarkers, TumorCirculating Tumor DNAcirculating tumor DNA (ctDNA)liquid biopsyLymphomasnext generation sequencing (NGS)

Identifiers

PMID39126310
PMCPMC11627208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.