Evidence map›Paper›PMID 39126266›Full record

ArticleAnnals of medicine2024

Hospitalized children with COVID-19 infection during large outbreak of SARS-CoV-2 Omicron strain: a retrospective study in Chaozhou, Guangdong, China.

Fen Lin, Man-Tong Chen, Lin Zhang, He Xie, Zhe Yang, Bin Huang, Jian-Peng Wu, Wei-Hao Lin, Li-Ye Yang

Abstract read
In one paragraph

Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. COVID-19 evolution in pediatric emergency department patients in Madrid, Spain: a single-center, retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fen LinPrecision Medical Lab Center, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Man-Tong ChenPrecision Medical Lab Center, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Lin ZhangPrecision Medical Lab Center, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
He XieDepartment of Pediatrics, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Zhe YangDepartment of Pediatrics, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Bin HuangDepartment of Pediatrics, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Jian-Peng WuDepartment of Pediatrics, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Wei-Hao LinDepartment of Pediatrics, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, PR China.
Li-Ye YangPrecision Medical Lab Center, People's Hospital of Yangjiang, Yangjiang, PR China.ORCID 0000-0003-1581-9089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate the clinical findings of hospitalized paediatric COVID-19 patients by the end of 2022.

methodAll confirmed children with COVID-19 infection admitted into Chaozhou Central Hospital during the COVID-19 outbreak from 19 December 2022 to 1 February 2023 were included. Detailed clinical data of those children were evaluated retrospectively.

resultsA total of 286 children, ranging in age from 1 month to 13 years old, were diagnosed with SARS-CoV-2 infection. Among these cases, 138 (48.3%) were categorized as mild, 126 (44.0%) as moderate and 22 (7.7%) as severe/critical. Symptoms varied among the children and included fever, upper respiratory tract symptoms, convulsions, sore throat, poor appetite, dyspnoea and gastrointestinal symptoms. Notably, febrile convulsions were observed in 96 (33.6%) patients, while acute laryngitis was documented in 50 (17.5%) cases. Among the severe/critical patients, eight developed multisystem inflammatory syndrome in children (MIS-C), and tragically, one patient's condition worsened and resulted in death. Furthermore, MRI scans revealed abnormal brain signals in six severe/critical patients. The severe/critical group also exhibited more pronounced laboratory abnormalities, including decreased haemoglobin and elevated ALT, AST, LDH and CK levels.

conclusionsFebrile convulsions and acute laryngitis are frequently observed in children diagnosed with SARS-CoV-2 Omicron infection. Moreover, MIS-C and abnormal neuroimaging appear to be relatively common phenomena in severe/critical cases.

Indexed as

COVID-19SARS-CoV-2AdolescentChildChild, PreschoolChinaDisease OutbreaksFemaleHospitalizationHumansInfantMaleRetrospective StudiesSeverity of Illness Indexclinical characteristicsfebrile convulsionsmultisystem inflammatory syndrome in children (MIS-C)Omicron wavepaediatric patients

Identifiers

PMID39126266
PMCPMC11318479

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