Evidence map›Paper›PMID 39126122›Full record

ArticleInternational journal of molecular sciences2024

Genetic Polymorphisms and Genetic Risk Scores Contribute to the Risk of Coronary Artery Disease (CAD) in a North Indian Population.

Sarabjit Mastana, Kushni Charisma Halai, Liz Akam, David John Hunter, Puneetpal Singh

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarabjit MastanaSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0002-9553-4886
Kushni Charisma HalaiSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.
Liz AkamSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0002-8784-3742
David John HunterSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough LE11 3TU, UK.ORCID 0000-0003-1060-3334
Puneetpal SinghDepartment of Human Genetics, Punjabi University, Patiala 147002, India.ORCID 0000-0003-2154-4261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) is the leading cause of death in India. Many genetic polymorphisms play a role in regulating oxidative stress, blood pressure and lipid metabolism, contributing to the pathophysiology of CAD. This study examined the association between ten polymorphisms and CAD in the Jat Sikh population from Northern India, also considering polygenic risk scores. This study included 177 CAD cases and 175 healthy controls. The genetic information of

Indexed as

AngiotensinogenApolipoprotein A-VApolipoproteins ECoronary Artery DiseaseGenetic Risk ScoreGlutathione TransferasePolymorphism, Single NucleotideAgedApolipoprotein C-IIICase-Control StudiesFemaleGene FrequencyGenetic Association StudiesHaplotypesHumansIndiaACE protein, humanAGT protein, humanAGTR1 protein, humanAngiotensinogenAPOA5 protein, humanAPOC3 protein, humanApoE protein, humanApolipoprotein A-VApolipoprotein C-IIIApolipoproteins Eglutathione S-transferase T1Glutathione TransferasePeptidyl-Dipeptidase AReceptor, Angiotensin, Type 1ACEAGT M235TAGTR1 A1166CAGT T174MAPOA5APOECADGST*M1GST*T1haplotypesNorth Indiapolygenic risk score

Identifiers

PMID39126122
PMCPMC11313018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.