Evidence map›Paper›PMID 39126071›Full record

ArticleInternational journal of molecular sciences2024

Utilizing Deep Neural Networks to Fill Gaps in Small Genomes.

Yu Chen, Gang Wang, Tianjiao Zhang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu ChenCollege of Computer and Control Engineering, Northeast Forestry University, Harbin 150040, China.
Gang WangCollege of Computer and Control Engineering, Northeast Forestry University, Harbin 150040, China.
Tianjiao ZhangCollege of Computer and Control Engineering, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0001-9807-8620

Funding

Tianjiao Zhang 62172087
6 · The paper itself

Abstract

With the widespread adoption of next-generation sequencing technologies, the speed and convenience of genome sequencing have significantly improved, and many biological genomes have been sequenced. However, during the assembly of small genomes, we still face a series of challenges, including repetitive fragments, inverted repeats, low sequencing coverage, and the limitations of sequencing technologies. These challenges lead to unknown gaps in small genomes, hindering complete genome assembly. Although there are many existing assembly software options, they do not fully utilize the potential of artificial intelligence technologies, resulting in limited improvement in gap filling. Here, we propose a novel method, DLGapCloser, based on deep learning, aimed at assisting traditional tools in further filling gaps in small genomes. Firstly, we created four datasets based on the original genomes of

Indexed as

Neural Networks, ComputerAlgorithmsDeep LearningGenome, FungalGenomicsHigh-Throughput Nucleotide SequencingNeurospora crassaSaccharomyces cerevisiaeSchizosaccharomycesSequence Analysis, DNASoftwaregap closinggap fillingnext-generation sequencingNLP

Identifiers

PMID39126071
PMCPMC11313336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.