Evidence map›Paper›PMID 39126048›Full record

ArticleInternational journal of molecular sciences2024

Biological Properties of Oleanolic Acid Derivatives Bearing Functionalized Side Chains at C-3.

Gianfranco Fontana, Natale Badalamenti, Maurizio Bruno, Filippo Maggi, Federica Dell'Annunziata, Nicoletta Capuano, Mario Varcamonti, Anna Zanfardino

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gianfranco FontanaDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.
Natale BadalamentiDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0001-7961-3894
Maurizio BrunoDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0003-0583-0487
Filippo MaggiChemistry Interdisciplinary Project (ChIP) Research Center, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, Italy.ORCID 0000-0003-1375-4744
Federica Dell'AnnunziataDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-1654-8500
Nicoletta CapuanoDepartment of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.
Mario VarcamontiDepartment of Biology, University of Naples, Federico II, Via Cinthia, 80126 Naples, Italy.
Anna ZanfardinoDepartment of Biology, University of Naples, Federico II, Via Cinthia, 80126 Naples, Italy.ORCID 0000-0002-6689-8365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triterpene acids are a class of pentacyclic natural carboxylic compounds endowed with a variety of biological activities including antitumor, antimicrobial, and hepatoprotective effects. In this work, several oleanolic acid derivatives were synthesized by structurally modifying them on the C-3 position. All synthesized derivatives were evaluated for possible antibacterial and antiviral activity, and among all the epimers,

Indexed as

Anti-Bacterial AgentsAntiviral AgentsEscherichia coliMicrobial Sensitivity TestsOleanolic AcidAnimalsHumansSARS-CoV-2Staphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAntiviral AgentsOleanolic Acidantibacterial activityoleanolic acidPV-1SARS-CoV-2triterpene derivatives

Identifiers

PMID39126048
PMCPMC11312724

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.