Evidence map›Paper›PMID 39126039›Full record

ArticleInternational journal of molecular sciences2024

Formononetin Defeats Multidrug-Resistant Cancers by Induction of Oxidative Stress and Suppression of P-Glycoprotein.

Ying-Tzu Chang, I-Ting Wu, Ming-Jyh Sheu, Yu-Hsuan Lan, Chin-Chuan Hung

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Formononetin: pharmacological properties and therapeutic potential.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  2. Article
  3. Review
  4. Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying-Tzu ChangDepartment of Pharmacy, China Medical University, No. 100, Section 1, Jingmao Road, Beitun District, Taichung 406040, Taiwan.
I-Ting WuDepartment of Pharmacy, China Medical University, No. 100, Section 1, Jingmao Road, Beitun District, Taichung 406040, Taiwan.
Ming-Jyh SheuDepartment of Pharmacy, China Medical University, No. 100, Section 1, Jingmao Road, Beitun District, Taichung 406040, Taiwan.
Yu-Hsuan LanDepartment of Pharmacy, China Medical University, No. 100, Section 1, Jingmao Road, Beitun District, Taichung 406040, Taiwan.
Chin-Chuan HungDepartment of Pharmacy, China Medical University, No. 100, Section 1, Jingmao Road, Beitun District, Taichung 406040, Taiwan.ORCID 0000-0003-1395-4834

Funding

China Medical University CMU112-N-22National Science and Technology Council NSTC 112-2320-B-039-031National Science and Technology Council NSTC 113-2320-B-039-012
6 · The paper itself

Abstract

Multidrug resistance (MDR) remains the most difficult problem facing conventional chemotherapy for cancers.

Indexed as

DoxorubicinDrug Resistance, MultipleDrug Resistance, NeoplasmIsoflavonesMolecular Docking SimulationOxidative StressAnimalsATP Binding Cassette Transporter, Subfamily B, Member 1Cell Line, TumorCell SurvivalDrug SynergismHumansMembrane Potential, MitochondrialMiceNeoplasmsXenograft Model Antitumor AssaysATP Binding Cassette Transporter, Subfamily B, Member 1DoxorubicinformononetinIsoflavonesformononetinmultidrug resistance canceroxidative stressP-glycoprotein

Identifiers

PMID39126039
PMCPMC11312483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.