ReviewInternational journal of molecular sciences2024
Redox Chemistry: Implications for Necrotizing Enterocolitis.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- AI-2 combined with Lactobacillus rhamnosus GG remodels gut microbiota structure to alleviate intestinal oxidative stress injury in a mouse necrotizing enterocolitis model.Journal of translational medicine · 2026Article
- Oxidative Stress and Necrotizing Enterocolitis in Preterm Newborns: The Role of GSTM1 and GSTT1 Null Genotypes.Biomolecules · 2026Article
- Sildenafil pretreatment attenuates apoptosis and intestinal injury in a hypoxia-ischemia-induced NEC-like rat model.Scientific reports · 2026Article
- Transcriptome, metabolome, and inflammatory and oxidative properties ofApplied and environmental microbiology · 2026Article
- ALAS2 Prevents Neonatal Necrotizing Enterocolitis by Improving Ferroptosis in Intestinal Epithelial Cells Through Inhibition of Oxidative Stress.Mediators of inflammation · 2026Article
- Oxidative Stress in Neonatal Disease: Established Organ Injury and Emerging Evidence for Skeletal Involvement.Oxidative medicine and cellular longevity · 2026Review
- Dietary Glycyl-Glutamine Supplementation Improves Growth, Immunity, Antioxidant Capacity, and Apparent Digestibility of Weaned Piglets.Animals : an open access journal from MDPI · 2025Article
- Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage.Clinical and translational medicine · 2025Article
- Elevated DUOX2 levels correlate with necrotizing enterocolitis development.Frontiers in cellular and infection microbiology · 2025Article
- Data-independent acquisition-based blood proteomics unveils predictive biomarkers for neonatal necrotizing enterocolitis.Analytical and bioanalytical chemistry · 2025Article
- Comprehensive Characterization of the Oxidative Stress Profiles in Neonatal Necrotizing Enterocolitis.International journal of medical sciences · 2025Article
- [Research progress on the pathological mechanisms and clinical translation of ferroptosis in necrotizing enterocolitis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsReview
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reduction-oxidation (redox) chemistry plays a vital role in human homeostasis. These reactions play critical roles in energy generation, as part of innate immunity, and in the generation of secondary messengers with various functions such as cell cycle progression or the release of neurotransmitters. Despite this cornerstone role, if left unchecked, the body can overproduce reactive oxygen species (ROS) or reactive nitrogen species (RNS). When these overwhelm endogenous antioxidant systems, oxidative stress (OS) occurs. In neonates, OS has been associated with retinopathy of prematurity (ROP), leukomalacia, and bronchopulmonary dysplasia (BPD). Given its broad spectrum of effects, research has started to examine whether OS plays a role in necrotizing enterocolitis (NEC). In this paper, we will discuss the basics of redox chemistry and how the human body keeps these in check. We will then discuss what happens when these go awry, focusing mostly on NEC in neonates.
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Registered trials
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