Evidence map›Paper›PMID 39125977›Full record

ArticleInternational journal of molecular sciences2024

New Generation of Orthodontic Elastomeric Ligature to Prevent Enamel Demineralization In Vivo.

Ce Bian, Menghao Lyu, Mengyao Zhu, Chaoran Yu, Yiman Guo, Michael D Weir, Radi Masri, Yuxing Bai, Hockin H K Xu, Ning Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ce BianDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Menghao LyuDepartment of Periodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Mengyao ZhuDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Chaoran YuDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Yiman GuoDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Michael D WeirDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, University of Maryland, Baltimore, MD 21201, USA.
Radi MasriDepartment of Advanced Oral Sciences and Therapeutics, University of Maryland School of Dentistry, University of Maryland, Baltimore, MD 21201, USA.
Yuxing BaiDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.
Hockin H K XuDepartment of Biomaterials and Regenerative Dental Medicine, University of Maryland School of Dentistry, University of Maryland, Baltimore, MD 21201, USA.
Ning ZhangDepartment of Orthodontics, School of Stomatology, Capital Medical University, Beijing 100050, China.

Funding

Innovation Research Team Project of Beijing Stomatological Hospital, Capital Medical University CXTD202203National Natural Science Foundation of China 82370989
6 · The paper itself

Abstract

This study aimed to synthesize a novel elastomeric ligature with dimethylaminohexadecyl methacrylate (DMAHDM) grafted, providing a new strategy for improving the issue of enamel demineralization during fixed orthodontics. DMAHDM was incorporated into elastomeric ligatures at different mass fractions using ultraviolet photochemical grafting. The antibacterial properties were evaluated and the optimal DMAHDM amount was determined based on cytotoxicity assays. Moreover, tests were conducted to evaluate the in vivo changes in the mechanical properties of the elastomeric ligatures. To assess the actual in vivo effectiveness in preventing enamel demineralization, a rat demineralization model was established, with analyses focusing on changes in surface microstructure, elemental composition, and nanomechanical properties. Elastomeric ligatures with 2% DMAHDM showed excellent biocompatibility and the best antibacterial properties, reducing lactic acid production by 65.3% and biofilm bacteria by 50.0% within 24 h, without significant mechanical property differences from the control group (

Indexed as

Dental EnamelElastomersTooth DemineralizationAnimalsAnti-Bacterial AgentsBiofilmsMaleMethacrylatesOrthodontic AppliancesRatsAnti-Bacterial AgentsElastomersMethacrylatesantibacterial propertieselastomeric ligatureenamel demineralizationmechanical propertiesorthodontics

Identifiers

PMID39125977
PMCPMC11313520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.