Evidence map›Paper›PMID 39125973›Full record

ArticleInternational journal of molecular sciences2024

Novel Identification of Ankyrin-R in Cardiac Fibroblasts and a Potential Role in Heart Failure.

Aaron D Argall, Holly C Sucharski-Argall, Luke G Comisford, Sallie J Jurs, Jack T Seminetta, Michael J Wallace, Casey A Crawford, Sarah S Takenaka, Mei Han, Mona El Refaey and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aaron D ArgallFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Holly C Sucharski-ArgallFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-0051-2474
Luke G ComisfordFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Sallie J JursFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Jack T SeminettaFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Michael J WallaceFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Casey A CrawfordFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Sarah S TakenakaDivision of Cardiac Surgery, Department of Surgery, Ohio State University, Columbus, OH 43210, USA.
Mei HanFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Mona El RefaeyDivision of Cardiac Surgery, Department of Surgery, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3989-0920
Thomas J HundFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-9957-7306
Peter J MohlerFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.
Sara N KoenigFrick Center for Heart Failure and Arrhythmia Research, Dorothy M. Davis Heart and Lung Research Institute, Wexner Medical Center, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-5416-8621

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Defining novel mechanisms for human arrhythmiaR35HL135754 · NHLBI · OHIO STATE UNIVERSITY · PI MOHLER, PETER J. · 2017 to 2023
$6.0M
Distinct Ion Channel Pools and Intercalated Disk Nanoscale Structure Regulate Cardiac ConductionR01HL165751 · NHLBI · OHIO STATE UNIVERSITY · PI Thomas Jeffrey Hund, Rengasayee Veeraraghavan · 2023 to 2026
$2.9M
Novel Roles of Protein phosphatase 2A in Cardiac ArrhythmiaR01HL175380 · NHLBI · OHIO STATE UNIVERSITY · PI Mona El Refaey · 2024 to 2026
$1.9M
Role of TREK-1 in modulating cardiac excitability and arrhythmiaR01HL156652 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2021 to 2024
$1.7M
Novel role for the spectrin cytoskeleton in regulation of cardiac fibroblast activity, long-range communication and injury-induced fibrosisR01HL171689 · NHLBI · OHIO STATE UNIVERSITY · PI Thomas Jeffrey Hund · 2024 to 2026
$1.6M
Spectrin-based regulation of cardiac remodeling and heart failureR01HL135096 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2017 to 2020
$1.6M
Defining new pathways for cardiac automaticityR00HL146969 · NHLBI · OHIO STATE UNIVERSITY · PI EL REFAEY, MONA · 2021 to 2023
$747k
Defining new pathways for cardiac automaticityK99HL146969 · NHLBI · OHIO STATE UNIVERSITY · PI EL REFAEY, MONA · 2019 to 2020
$194k
NCI NIH HHS P30 CA016058NHLBI NIH HHS K99 HL146969NHLBI NIH HHS R00 HL146969NHLBI NIH HHS R01 HL135096NHLBI NIH HHS R01 HL156652NHLBI NIH HHS R01 HL165751NHLBI NIH HHS R01 HL171689NHLBI NIH HHS R01 HL175380NHLBI NIH HHS R35 HL135754NIH HHS 5R35HL135754-07A7
6 · The paper itself

Abstract

Altered ankyrin-R (AnkR; encoded by

Indexed as

AnkyrinsFibroblastsHeart FailureMice, KnockoutAnimalsFibrosisMaleMiceMice, Inbred C57BLMyocardiumMyocytes, CardiacAnk1 protein, mouseAnkyrinsAnkyrin-Rcardiomyocytefibroblastfibrosisheart failure

Identifiers

PMID39125973
PMCPMC11313496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.