Evidence map›Paper›PMID 39125957›Full record

ArticleInternational journal of molecular sciences2024

Proteomic Profiling of Tears in Blau Syndrome Patients in Identification of Potential Disease Biomarkers.

Paola Galozzi, Sara Bindoli, Chiara Baggio, Ilaria Battisti, Andrea Leonardi, Daniela Basso, Giorgio Arrigoni, Paolo Sfriso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paola GalozziLaboratory Medicine Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0002-8228-2069
Sara BindoliRheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Chiara BaggioRheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Ilaria BattistiDepartment of Biomedical Sciences, University of Padova, 35128 Padova, Italy.ORCID 0009-0000-5561-6804
Andrea LeonardiOphthalmology Unit, Department of Neuroscience, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-7246-8580
Daniela BassoLaboratory Medicine Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0001-8745-6171
Giorgio ArrigoniDepartment of Biomedical Sciences, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-4103-2733
Paolo SfrisoRheumatology Unit, Department of Medicine DIMED, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.ORCID 0000-0001-6432-7174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blau syndrome (BS) is a rare autoinflammatory granulomatosis characterized by granulomatous arthritis, uveitis, and dermatitis. Ocular complications are particularly severe in BS, significantly contributing to morbidity. This study aims to identify potential biomarkers for BS ocular degeneration through proteomic profiling of tear samples from affected patients. Seven subjects from the same family, including four carriers of the BS-associated

Indexed as

ArthritisBiomarkersProteomicsSarcoidosisSynovitisTearsUveitisAdultFemaleHereditary Autoinflammatory DiseasesHumansMaleMiddle AgedMutationNod2 Signaling Adaptor ProteinProteomeBiomarkersNOD2 protein, humanNod2 Signaling Adaptor ProteinProteomeautoinflammatory diseasebiomarkersBlau syndromeproteomicstear fluidsuveitis

Identifiers

PMID39125957
PMCPMC11312868

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.