Evidence map›Paper›PMID 39125946›Full record

ArticleInternational journal of molecular sciences2024

Immunological Profiling of CD8

Laszlo Szereday, David U Nagy, Fanni Vastag, Livia Mezosi, Matyas Meggyes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laszlo SzeredayDepartment of Medical Microbiology and Immunology, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.ORCID 0000-0002-1208-2969
David U NagyInstitute of Geobotany/Plant Ecology, Martin-Luther-University, Große Steinstraße 79/80, D-06108 Halle (Saale), Germany.ORCID 0000-0001-7742-4459
Fanni VastagDepartment of Obstetrics and Gynaecology, Medical School, University of Pécs, 7624 Pécs, Hungary.
Livia MezosiDepartment of Medical Microbiology and Immunology, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.
Matyas MeggyesDepartment of Medical Microbiology and Immunology, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, Hungary.ORCID 0000-0002-9913-2024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the numerous studies on the clinical aspects of early-onset preeclampsia, our understanding of the immunological consequences of inadequate placenta development remains incomplete. The Th1-predominance characteristic of early-onset preeclampsia significantly impacts maternal immunotolerance, and the role of immune checkpoint molecules in these mechanisms is yet to be fully elucidated. Our study aims to fill these crucial knowledge gaps. A total of 34 pregnant women diagnosed with early-onset preeclampsia and 34 healthy pregnant women were enrolled in this study. A mononuclear cell fragment from the venous blood was separated and frozen. The CD8

Indexed as

CD8-Positive T-LymphocytesKiller Cells, NaturalPre-EclampsiaAdultAntigens, Differentiation, T-LymphocyteCase-Control StudiesFemaleHumansImmune Checkpoint ProteinsPregnancyT Lineage-Specific Activation Antigen 1Antigens, Differentiation, T-LymphocyteImmune Checkpoint ProteinsT Lineage-Specific Activation Antigen 1CD226CD8early-onset preeclampsiaimmune checkpoint pathwaysLAG-3NK cellsTIGIT

Identifiers

PMID39125946
PMCPMC11313567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.