Evidence map›Paper›PMID 39125929›Full record

ArticleInternational journal of molecular sciences2024

Fungicide-Loaded Liposomes for the Treatment of Fungal Diseases in Agriculture: An Assessment of

Angelo Agnusdei, Anna Maria Maurelli, Donato Gerin, Donato Monopoli, Stefania Pollastro, Lucia Catucci, Francesco Faretra, Vincenzo De Leo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angelo AgnusdeiDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Via Amendola 165/A, 70126 Bari, Italy.ORCID 0009-0001-9916-0391
Anna Maria MaurelliDepartment of Chemistry, University of Bari Aldo Moro, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0001-9124-0007
Donato GerinDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Via Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0002-6520-2311
Donato MonopoliDepartment of Chemistry, University of Bari Aldo Moro, Via Orabona 4, 70126 Bari, Italy.
Stefania PollastroDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Via Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0001-8806-1905
Lucia CatucciDepartment of Chemistry, University of Bari Aldo Moro, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0003-2206-9247
Francesco FaretraDepartment of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Via Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0003-1063-0607
Vincenzo De LeoDepartment of Chemistry, University of Bari Aldo Moro, Via Orabona 4, 70126 Bari, Italy.ORCID 0000-0001-7363-1899

Funding

Università di Bari -Italy HORIZON EUROPE SEEDS -S28 (Sos&Bio_for_One Health)
6 · The paper itself

Abstract

In this work, liposomes loaded with the fungicide, Fludioxonil (FLUD), for the containment of fungal diseases in agriculture were developed. Three types of vesicles with different compositions were compared: (I) plain vesicles, composed of soy phosphatidylcholine and cholesterol; (II) PEG-coated vesicles, with an additional polyethylene glycol coating; and (III) cationic vesicles, containing didodecyldimethylammonium bromide. Nanometric-sized vesicles were obtained both by the micelle-to-vesicle transition method and by the extrusion technique, and encapsulation efficiency, drug loading content, and Zeta potential were determined for all the samples. The extruded and PEGylated liposomes were the most stable over time and together with the cationic ones showed a significant prolonged FLUD release capacity. The liposomes' biological activity was evaluated on conidial germination, germ tube elongation and colony radial growth of the ascomycete

Indexed as

BotrytisDioxolesFungicides, IndustrialLiposomesPlant DiseasesAgriculturePhosphatidylcholinesPolyethylene GlycolsPyrrolesQuaternary Ammonium CompoundsSpores, FungaldidodecyldimethylammoniumDioxolesfludioxonilFungicides, IndustrialLiposomesPhosphatidylcholinesPolyethylene GlycolsPyrrolesQuaternary Ammonium CompoundsagricultureBotrytis cinereacolony radial growthconidial germination testFludioxonilfungal diseasesfungicidegerm tube elongationliposome

Identifiers

PMID39125929
PMCPMC11313257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.