Evidence map›Paper›PMID 39125877›Full record

ArticleInternational journal of molecular sciences2024

An Optimized Peptide Antagonist of CXCR4 Limits Survival of BCR-ABL1-Transformed Cells in Philadelphia-Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia.

Johanna Pohl, Angela Litz, Omar El Ayoubi, Armando Rodríguez-Alfonso, Ludger Ständker, Mirja Harms, Jan Münch, Hassan Jumaa, Moumita Datta

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johanna PohlInstitute of Immunology, Ulm University Medical Center, 89081 Ulm, Germany.
Angela LitzInstitute of Immunology, Ulm University Medical Center, 89081 Ulm, Germany.
Omar El AyoubiInstitute of Immunology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0009-0003-3204-6775
Armando Rodríguez-AlfonsoCore Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ludger StändkerCore Facility Functional Peptidomics, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Mirja HarmsInstitute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0002-5460-5166
Jan MünchInstitute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-7316-7141
Hassan JumaaInstitute of Immunology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0003-3383-141X
Moumita DattaInstitute of Immunology, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0009-0004-6524-4804

Funding

Deutsche Forschungsgemeinschaft CRC1279
6 · The paper itself

Abstract

Philadelphia-chromosome-positive acute lymphoblastic leukemia (Ph

Indexed as

Fusion Proteins, bcr-ablReceptors, CXCR4AnimalsApoptosisCell Line, TumorCell SurvivalHumansMicePeptidesPhiladelphia ChromosomePrecursor B-Cell Lymphoblastic Leukemia-LymphomaPrecursor Cell Lymphoblastic Leukemia-LymphomaCXCR4 protein, humanFusion Proteins, bcr-ablPeptidesReceptors, CXCR4AMD3100BCR–ABL1cell survivalCXCR4EPI-X4 derivativesImatinib

Identifiers

PMID39125877
PMCPMC11312813

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.