Evidence map›Paper›PMID 39125811›Full record

ArticleInternational journal of molecular sciences2024

Nuclear Factor-Kappa-B Mediates the Advanced Glycation End Product-Induced Repression of

Maria Luiza Estimo Michalani, Marisa Passarelli, Ubiratan Fabres Machado

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The role of bone in whole-body energy metabolism.Nature reviews. Endocrinology · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Luiza Estimo MichalaniDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-7914-0107
Marisa PassarelliLaboratório de Lípides (LIM-10) do HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 01246-000, SP, Brazil.ORCID 0000-0002-9249-4698
Ubiratan Fabres MachadoDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-8237-2435

Funding

Fundação de apoio a Pesquisa Estado São Paulo - FAPESP 2016/15603-0
6 · The paper itself

Abstract

Advanced glycated end products (AGEs) are cytotoxic compounds that are mainly increased in diabetes mellitus (DM), kidney failure, inflammation, and in response to the ingestion of AGE-rich diets. AGEs can also impair glycemic homeostasis by decreasing the expression of the

Indexed as

3T3-L1 CellsAdipocytesGlucose Transporter Type 4Glycation End Products, AdvancedTranscription Factor RelAAnimalsGene Expression RegulationMiceNF-kappa BNF-kappa B p50 SubunitPromoter Regions, GeneticGlucose Transporter Type 4Glycation End Products, AdvancedNF-kappa BNF-kappa B p50 SubunitNfkb1 protein, mouseRela protein, mouseSlc2a4 protein, mouseTranscription Factor RelA3T3L1 adipocyteadvanced glycation end productsdiabetes mellitusGLUT4inflammatory activityNFKB

Identifiers

PMID39125811
PMCPMC11311564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.