Evidence map›Paper›PMID 39125681›Full record

ArticleInternational journal of molecular sciences2024

High-Throughput Molecular Modeling and Evaluation of the Anti-Inflammatory Potential of Açaí Constituents against NLRP3 Inflammasome.

Elaine Cristina Medeiros da Rocha, João Augusto Pereira da Rocha, Renato Araújo da Costa, Andreia do Socorro Silva da Costa, Edielson Dos Santos Barbosa, Luiz Patrick Cordeiro Josino, Luciane do Socorro Nunes Dos Santos Brasil, Laura Fernanda Osmari Vendrame, Alencar Kolinski Machado, Solange Binotto Fagan and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elaine Cristina Medeiros da RochaLaboratory of Modeling and Computational Chemistry, Federal Institute of Education, Science and Technology of Pará (IFPA) Campus Bragança, Bragança 68600-000, PA, Brazil.
João Augusto Pereira da RochaLaboratory of Modeling and Computational Chemistry, Federal Institute of Education, Science and Technology of Pará (IFPA) Campus Bragança, Bragança 68600-000, PA, Brazil.ORCID 0000-0002-3178-2362
Renato Araújo da CostaLaboratory of Biosolutions and Bioplastics of the Amazon, Graduate Program in Science and Environment, Institute of Exact and Natural Sciences, Federal University of Pará (UFPA), Belém 66075-110, PA, Brazil.ORCID 0000-0002-4720-6116
Andreia do Socorro Silva da CostaLaboratory of Biosolutions and Bioplastics of the Amazon, Graduate Program in Science and Environment, Institute of Exact and Natural Sciences, Federal University of Pará (UFPA), Belém 66075-110, PA, Brazil.
Edielson Dos Santos BarbosaLaboratory of Biosolutions and Bioplastics of the Amazon, Graduate Program in Science and Environment, Institute of Exact and Natural Sciences, Federal University of Pará (UFPA), Belém 66075-110, PA, Brazil.
Luiz Patrick Cordeiro JosinoLaboratório de Planejamento e Desenvolvimento de Fármacos, Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará, Belém 66075-110, PA, Brazil.
Luciane do Socorro Nunes Dos Santos BrasilLaboratory of Biosolutions and Bioplastics of the Amazon, Graduate Program in Science and Environment, Institute of Exact and Natural Sciences, Federal University of Pará (UFPA), Belém 66075-110, PA, Brazil.
Laura Fernanda Osmari VendrameGraduate Program in Nanosciences, Franciscana University, Santa Maria 97010-032, RS, Brazil.
Alencar Kolinski MachadoGraduate Program in Nanosciences, Franciscana University, Santa Maria 97010-032, RS, Brazil.
Solange Binotto FaganGraduate Program in Nanosciences, Franciscana University, Santa Maria 97010-032, RS, Brazil.ORCID 0000-0001-7878-1212
Davi do Socorro Barros BrasilLaboratory of Biosolutions and Bioplastics of the Amazon, Graduate Program in Science and Environment, Institute of Exact and Natural Sciences, Federal University of Pará (UFPA), Belém 66075-110, PA, Brazil.ORCID 0000-0002-1461-7306

Funding

PROPESP/UFPA PROPESP/UFPA
6 · The paper itself

Abstract

The search for bioactive compounds in natural products holds promise for discovering new pharmacologically active molecules. This study explores the anti-inflammatory potential of açaí (

Indexed as

Anti-Inflammatory AgentsInflammasomesMolecular Docking SimulationMolecular Dynamics SimulationNLR Family, Pyrin Domain-Containing 3 ProteinEuterpeHumansPlant ExtractsAnti-Inflammatory AgentsInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanPlant Extractsaçaí (Euterpe oleracea)anti-inflammatoryin silico toxicologyMM/GBSAmolecular dockingmolecular dynamics simulationsNLRP3 inflammasome

Identifiers

PMID39125681
PMCPMC11311378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.