Evidence map›Paper›PMID 39125660›Full record

ArticleInternational journal of molecular sciences2024

Biologically Active Sheep Colostrum for Topical Treatment and Skin Care.

Kinga Kazimierska, Ilona Szabłowska-Gadomska, Stefan Rudziński, Katarzyna Kośla, Elżbieta Płuciennik, Łukasz Bobak, Aleksandra Zambrowicz, Urszula Kalinowska-Lis

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kinga KazimierskaDepartment of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0009-0005-3461-9113
Ilona Szabłowska-GadomskaLaboratory for Cell Research and Application, Center for Preclinical Research and Technology, Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.ORCID 0000-0002-8649-1503
Stefan RudzińskiLaboratory for Cell Research and Application, Center for Preclinical Research and Technology, Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.ORCID 0000-0002-1122-5796
Katarzyna KoślaDepartment of Molecular Carcinogenesis, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-3603-0063
Elżbieta PłuciennikDepartment of Functional Genomics, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-6682-0402
Łukasz BobakDepartment of Functional Food Products Development, Wroclaw University of Environmental and Life Science, 51-640 Wrocław, Poland.ORCID 0000-0002-4332-7252
Aleksandra ZambrowiczDepartment of Functional Food Products Development, Wroclaw University of Environmental and Life Science, 51-640 Wrocław, Poland.ORCID 0000-0002-4781-5296
Urszula Kalinowska-LisDepartment of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0003-3023-6105

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colostrum is gaining popularity in cosmetic products. The present study compared the composition and selected biological properties of colostrum from Polish sheep (colostrum 1) and Swiss sheep (colostrum 2), particularly those that can affect healthy or diseased skin. The antioxidant activity of the colostrums was measured using ABTS and DPPH assays. The effect on the proliferation of human skin fibroblasts, neonatal epidermal keratinocytes, and human diabetic fibroblast (dHF) cells isolated from diabetic foot ulcers was also assayed in vitro by MTT and Presto Blue tests, respectively. The colostrum simulated dHF cell proliferation by up to 115.4%. The highest used concentration of colostrum 1 stimulated normal fibroblast proliferation by 191.2% (24 h) and 222.2% (48 h). Both colostrums inhibited epidermal keratinocyte viability. The influence of the colostrums on the expression of genes related to proliferation (

Indexed as

Cell ProliferationColostrumFibroblastsKeratinocytesSkin CareAdministration, TopicalAnimalsAntioxidantsCells, CulturedCell SurvivalDiabetic FootFemaleHumansPregnancySheepSkinAntioxidantsantioxidantcosmetic ingredientsfibroblastsgene expressionkeratinocytesproliferationscar testsheep colostrumskin diseases

Identifiers

PMID39125660
PMCPMC11311297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.