Evidence map›Paper›PMID 39125613›Full record

ArticleInternational journal of molecular sciences2024

A Novel Affordable and Reliable Framework for Accurate Detection and Comprehensive Analysis of Somatic Mutations in Cancer.

Rossano Atzeni, Matteo Massidda, Enrico Pieroni, Vincenzo Rallo, Massimo Pisu, Andrea Angius

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rossano AtzeniCenter for Advanced Studies, Research and Development in Sardinia (CRS4), 09050 Pula, Italy.ORCID 0000-0003-0020-0013
Matteo MassiddaDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-5246-5585
Enrico PieroniCenter for Advanced Studies, Research and Development in Sardinia (CRS4), 09050 Pula, Italy.ORCID 0000-0002-4246-6963
Vincenzo RalloIstituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Cittadella Universitaria di Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-8938-5650
Massimo PisuCenter for Advanced Studies, Research and Development in Sardinia (CRS4), 09050 Pula, Italy.ORCID 0000-0002-8799-9106
Andrea AngiusIstituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Cittadella Universitaria di Cagliari, 09042 Monserrato, Italy.ORCID 0000-0003-2596-6461

Funding

Fondo di Beneficenza of Intesa Sanpaolo S.p.A. B/2020/0094Ministry of University and Research PRIN 2022WBLA3Z
6 · The paper itself

Abstract

Accurate detection and analysis of somatic variants in cancer involve multiple third-party tools with complex dependencies and configurations, leading to laborious, error-prone, and time-consuming data conversions. This approach lacks accuracy, reproducibility, and portability, limiting clinical application.

Indexed as

MutationNeoplasmsSoftwareComputational BiologyDNA Mutational AnalysisGenomicsHigh-Throughput Nucleotide SequencingHumansReproducibility of Resultscancermachine learningmutational patternsmutational signaturesprecision medicinesomatic mutationssomatic variant detection

Identifiers

PMID39125613
PMCPMC11311285

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.