Evidence map›Paper›PMID 39125605›Full record

ArticleInternational journal of molecular sciences2024

Association of SDF-1-3' Gene A Variant with Diabetic Retinopathy in the Hungarian Population.

Monika Ecsedy, Illes Kovacs, Andrea Szigeti, Hajnalka Horvath, Lilla Lenart, Zsuzsanna Recsan, Timea Medveczki, Zoltan Zsolt Nagy, Andrea Fekete

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monika EcsedyDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Illes KovacsDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Andrea SzigetiDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Hajnalka HorvathDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Lilla LenartMTA-SE Lendület Diabetes Research Group, Hungarian Academy of Sciences and Semmelweis University, 1085 Budapest, Hungary.
Zsuzsanna RecsanDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Timea MedveczkiMTA-SE Lendület Diabetes Research Group, Hungarian Academy of Sciences and Semmelweis University, 1085 Budapest, Hungary.
Zoltan Zsolt NagyDepartment of Ophthalmology, Semmelweis University Budapest, 1085 Budapest, Hungary.
Andrea FeketeMTA-SE Lendület Diabetes Research Group, Hungarian Academy of Sciences and Semmelweis University, 1085 Budapest, Hungary.

Funding

Hungarian Academy of Sciences LP2021-3/2021Ministry for Innovation and Technology OTKA-K135398Ministry for Innovation and Technology TKP2021-EGA-24
6 · The paper itself

Abstract

We investigated the association between the SDF-1-3' (c801G > A) variant and the development of diabetic macular edema (DME) or proliferative diabetic retinopathy (PDR) in a Hungarian cohort. SDF-1-3' (c801G > A) was genotyped in 103 patients with diabetic retinopathy and 31 age- and sex-matched non-diabetic controls. Central retinal and choroidal thickness was measured by swept-source optical coherence tomography. The distribution of heterozygous and homozygous SDF-1-3' (c801G > A) genotypes was similar in diabetic and control subjects. The SDF-3'(c801AA) genotype was associated with DME (

Indexed as

Chemokine CXCL12Diabetic RetinopathyAgedAllelesCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansHungaryMacular EdemaMaleMiddle AgedPolymorphism, Single NucleotideTomography, Optical CoherenceChemokine CXCL12CXCL12 protein, humancentral retinal thicknessdiabetic maculopathySDF-1-3′ (c801G > A) polymorphismstromal cell-derived factor 1

Identifiers

PMID39125605
PMCPMC11311494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.