Evidence map›Paper›PMID 39125594›Full record

ArticleInternational journal of molecular sciences2024

From Proteome to Potential Drugs: Integration of Subtractive Proteomics and Ensemble Docking for Drug Repurposing against

Gabriela Urra, Elizabeth Valdés-Muñoz, Reynier Suardiaz, Erix W Hernández-Rodríguez, Jonathan M Palma, Sofía E Ríos-Rozas, Camila A Flores-Morales, Melissa Alegría-Arcos, Osvaldo Yáñez, Luis Morales-Quintana and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gabriela UrraLaboratorio de Bioinformática y Química Computacional, Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca 3480094, Chile.ORCID 0009-0006-3871-0261
Elizabeth Valdés-MuñozDoctorado en Biotecnología Traslacional, Facultad de Ciencias Agrarias y Forestales, Universidad Católica del Maule, Talca 3480094, Chile.
Reynier SuardiazDepartamento de Química Física, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1035-9020
Erix W Hernández-RodríguezLaboratorio de Bioinformática y Química Computacional, Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca 3480094, Chile.
Jonathan M PalmaFacultad de Ingeniería, Universidad de Talca, Curicó 3344158, Chile.ORCID 0000-0002-3924-1907
Sofía E Ríos-RozasLaboratorio de Bioinformática y Química Computacional, Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca 3480094, Chile.
Camila A Flores-MoralesMagíster en Ciencias de la Computación, Universidad Católica del Maule, Talca 3460000, Chile.
Melissa Alegría-ArcosNúcleo de Investigación en Data Science, Facultad de Ingeniería y Negocios, Universidad de las Américas, Santiago 7500000, Chile.
Osvaldo YáñezNúcleo de Investigación en Data Science, Facultad de Ingeniería y Negocios, Universidad de las Américas, Santiago 7500000, Chile.ORCID 0000-0001-8993-9353
Luis Morales-QuintanaMultidisciplinary Agroindustry Research Laboratory, Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Cinco Pte. N° 1670, Talca 3467987, Chile.ORCID 0000-0002-7194-1989
Vívian D'AfonsecaDepartamento de Ciencias Preclínicas, Facultad de Medicina, Universidad Católica del Maule, Ave. San Miguel 3605, Talca 3466706, Chile.ORCID 0000-0002-1685-5260
Daniel BustosLaboratorio de Bioinformática y Química Computacional, Departamento de Medicina Traslacional, Facultad de Medicina, Universidad Católica del Maule, Talca 3480094, Chile.ORCID 0000-0002-2136-2305

Funding

ANID Fomento a la Vinculación Internacional para Instituciones de Investigación FOVI230136ANID FONDECYT de Iniciación en Investigación 11220444
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug RepositioningMolecular Docking SimulationProteomeProteomicsPseudomonas aeruginosaHumansSuraminAnti-Bacterial AgentsBacterial ProteinsProteomeSuraminantimicrobial resistancedrug repurposingefflux pumpensemble-dockingPseudomonas aeruginosaRND superfamilysubtractive proteomics

Identifiers

PMID39125594
PMCPMC11312079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.