Evidence map›Paper›PMID 39125550›Full record

ArticleDiagnostics (Basel, Switzerland)2024

The Effect of Therapeutic Hypothermia on Ischemic Brain Injury in a Rat Model of Cardiac Arrest: An Assessment Using

Daehee Kim, Woon Jeong Lee, Seon Hee Woo, Hye Won Lee, Bom Sahn Kim, Hai-Jeon Yoon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daehee KimDepartment of Emergency Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Republic of Korea.ORCID 0000-0001-5104-9806
Woon Jeong LeeDepartment of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Seon Hee WooDepartment of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Hye Won LeeDepartment of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Bom Sahn KimDepartment of Nuclear Medicine, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea.ORCID 0000-0003-2520-7182
Hai-Jeon YoonDepartment of Nuclear Medicine, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea.ORCID 0000-0001-8752-6280

Funding

a Grant of Transla- tional R&D Project through Institute for Bio-Medical convergence, Incheon St. Mary's Hospital, The Catholic University of Korea IBC-2021-01National Research Foundation of Korea 2021R1A2C1093636
6 · The paper itself

Abstract

purposeTherapeutic hypothermia (TH) is widely acknowledged as one of the interventions for preventing hypoxic ischemic brain injury in comatose patients following cardiac arrest (CA). Despite its recognized efficacy, recent debates have questioned its effectiveness. This preclinical study evaluated the impact of TH on brain glucose metabolism, utilizing fluorine-18-fluorodeoxyglucose (

methodsAsphyxia CA was induced in Sprague-Dawley rats using vecuronium. Brain PET images using

resultsSurvival rates were identical in both the TH and non-TH groups (67%). There was no discernible difference in the SUVR

conclusionsThe enhancement in SUVR

Indexed as

cardiac arrestfluorodeoxyglucose F18ischemic brain injurypositron emission tomography computed tomographytherapeutic hypothermia

Identifiers

PMID39125550
PMCPMC11311465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.