Evidence map›Paper›PMID 39125540›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Utilizing Next-Generation Sequencing: Advancements in the Diagnosis of Fungal Infections.

Sheetal Naik, Dharambir Kashyap, Jashan Deep, Saif Darwish, Joseph Cross, Edmond Mansoor, Vivek Kumar Garg, Prasanna Honnavar

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Microorganisms · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sheetal NaikDepartment of Physiology, American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.
Dharambir KashyapBrown Center for Immunotherapy, Melvin and Bren Simon Comprehensive Cancer Center, Division of Hematology and Oncology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.ORCID 0000-0002-9160-9377
Jashan DeepBasic Medical Science, American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.
Saif DarwishBasic Medical Science, American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.
Joseph CrossDepartment of Biochemistry, Cell Biology and Genetics; American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.
Edmond MansoorDepartment of Clinical Medicine; American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.
Vivek Kumar GargUniversity Institute of Allied Health Sciences, Chandigarh University, Gharuan, Mohali 140413, Punjab, India.ORCID 0000-0002-7906-2153
Prasanna HonnavarDepartment of Microbiology and Immunology; American University of Antigua College of Medicine, St. Johns 1451, Antigua and Barbuda.ORCID 0000-0003-3872-4242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation sequencing (NGS) has emerged as a promising tool for diagnosing fungal infections. It enables the identification of a wide range of fungal species and provides more accurate and rapid results than traditional diagnostic methods. NGS-based approaches involve the sequencing of DNA or RNA from clinical samples, which can be used to detect and identify fungal pathogens in complex clinical samples. The development of targeted gene panels and whole-genome sequencing has allowed for identifying genetic markers associated with antifungal drug resistance, enabling clinicians to tailor patient treatment options. NGS can also provide insights into the pathogenesis of fungal infections and aid in discovering novel drug targets. Although NGS has some limitations, such as cost and data analysis, it can potentially revolutionize the future diagnosis and treatment of fungal infections.

Indexed as

diagnosisfungal infectionnext-generation sequencingpneumonia

Identifiers

PMID39125540
PMCPMC11311512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.