Evidence map›Paper›PMID 39125535›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Incidence and Antenatal Detection of Congenital Heart Malformations-Data from a Tertiary Obstetric Romanian Center.

Adrian Ciulpan, Adrian Lacatușu, Liviu Laurenţiu Pop, Corina Paul, Diana Lungeanu, Daniela Iacob, Brenda-Cristiana Bernad, Ana Lascu, Edida Maghet, Diana-Aurora Arnautu and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adrian CiulpanDoctoral School, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0001-5796-4028
Adrian LacatușuIInd Pediatrics Clinic, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timișoara, Romania.
Liviu Laurenţiu PopIInd Pediatrics Clinic, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timișoara, Romania.
Corina PaulIInd Pediatrics Clinic, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timișoara, Romania.ORCID 0000-0001-9040-2297
Diana LungeanuCenter for Modeling Biological Systems and Data Analysis, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0002-0274-1377
Daniela IacobDepartment of Obstetrics and Gynecology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0003-2468-6003
Brenda-Cristiana BernadDoctoral School, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Ana LascuDepartment of Functional Sciences, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Edida MaghetIst Department, Faculty of Dental Medicine, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0009-0005-9704-3916
Diana-Aurora ArnautuMultidisciplinary Heart Research Center, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0001-9959-5718
Elena Silvia BernadDepartment of Obstetrics and Gynecology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.ORCID 0000-0003-1084-2714

Funding

"Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania support in covering the costs of publication for this research paper
6 · The paper itself

Abstract

objectivesCongenital heart defects (CHDs) are among the most frequent congenital defects, and they significantly burden the healthcare system due to their high mortality rate and high cost of care for survivors. We aimed to highlight the incidence of CHDs in a tertiary center in Western Romania.

methodsA retrospective study was carried out between 2018 and 2022 at the "Pius Brinzeu" Emergency County Hospital Timisoara. Relevant information about the mothers and the newborns were collected and statistically analyzed.

resultsThe incidence of CHDs from 2018 to 2022 in our center was 5.3%. Eleven types of malformations were diagnosed postnatally in 541 newborns, with 28.8% of cases having more than one type of CHD. The antenatal detection rate was 28%, with the highest rates for tetralogy of Fallot, hypoplastic left heart syndrome, or significant ventricular septal defects and the lowest for pulmonary stenosis. The lower antenatal detection rate was influenced mainly by incomplete or absent prenatal care.

conclusionsThe incidence of CHDs is clearly dependent of a multifactorial approach, and the results highlight this. With an incidence almost 50% lower than reported within the literature and a low rate of prenatal detections, CHDs could be a more of a burden to endure regarding medical treatment. Improvements in patients' education, prenatal care, and screening programs could improve diagnosis, decrease mortality, and optimize postnatal care.

Indexed as

congenital malformationdiagnosticheartincidenceprenatal ultrasound

Identifiers

PMID39125535
PMCPMC11311993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.