ArticleDiagnostics (Basel, Switzerland)2024
Shear-Wave Elastography Gradient Analysis of Newly Diagnosed Breast Tumours: A Critical Analysis.
Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Testicular Stiffness and Volume in Varicocele Patients: A Prospective Comparative Shear Wave Elastography Study.Diagnostics (Basel, Switzerland) · 2025Article
- Identification of differentiating sonographic features between fibroadenomas and malignant tumors of the breast mimicking fibroadenomas: 10-year experience in 421 histologically verified cases.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2025Article
- Diagnostic performance of ultrasound elastography in differentiating malignant from benign breast microcalcifications: a case-control study.BMC medical imaging · 2025Article
- BI-RADS application for breast cancer screening in primary healthcare settings: assessing protocol adherence and diagnostic validity.Frontiers in oncology · 2025Article
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9 authors.
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Abstract
backgroundA better understanding of the peritumoral stroma changes due to tumour invasion using non-invasive diagnostic methods may improve the differentiation between benign and malignant breast lesions. This study aimed to assess the correlation between breast lesion differentiation and intra- and peritumoral shear-wave elastography (SWE) gradients.
methodsA total of 135 patients with newly diagnosed breast lesions were included. Intratumoral, subsurface, and three consecutive peritumoral SWE value measurements (with three repetitions) were performed. Intratumoral, interface, and peritumoral gradients (Gradient 1 and Gradient 2) were calculated using averaged SWE values. Statistical analysis included descriptive statistics and an ordinary one-way ANOVA to compare overall and individual gradients among Breast Imaging-Reporting and Data System (BI-RADS) 2, 3, and 5 groups.
resultsMalignant tumours showed higher average SWE velocity values at the tumour centre (BI-RADS 2/3: 4.1 ± 1.8 m/s vs. BI-RADS 5: 4.9 ± 2.0 m/s,
conclusionsEvaluating the peritumoral SWE gradient may improve the diagnostic pre-test probability, as malignant tumours showed a significantly steeper curve of the elasticity values in the peritumoral stroma compared to the linear regression with a relatively flat curve of benign lesions.
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