Evidence map›Paper›PMID 39125463›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Endoscopic Ultrasound-Guided Through-the-Needle Biopsy: A Narrative Review of the Technique and Its Emerging Role in Pancreatic Cyst Diagnosis.

Filipe Vilas-Boas, Tiago Ribeiro, Guilherme Macedo, Jahnvi Dhar, Jayanta Samanta, Sokol Sina, Erminia Manfrin, Antonio Facciorusso, Maria Cristina Conti Bellocchi, Nicolò De Pretis and 2 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Endoscopic management of pancreatic cystic neoplasms.World journal of gastrointestinal oncology · 2025
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Filipe Vilas-BoasGastroenterology Department, Centro Hospitalar e Universitário de São João, Faculdade de Medicina da Universidade do Porto, 4200-349 Porto, Portugal.ORCID 0000-0001-7041-0863
Tiago RibeiroGastroenterology Department, Centro Hospitalar e Universitário de São João, Faculdade de Medicina da Universidade do Porto, 4200-349 Porto, Portugal.
Guilherme MacedoGastroenterology Department, Centro Hospitalar e Universitário de São João, Faculdade de Medicina da Universidade do Porto, 4200-349 Porto, Portugal.ORCID 0000-0002-9387-9872
Jahnvi DharDepartment of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Jayanta SamantaDepartment of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-9277-5086
Sokol SinaDepartment of Diagnostics and Public Health, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-3700-6989
Erminia ManfrinDepartment of Diagnostics and Public Health, University of Verona, 37129 Verona, Italy.
Antonio FacciorussoGastroenterology Unit, Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0002-2107-2156
Maria Cristina Conti BellocchiGastroenterology and Digestive Endoscopy Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0002-7813-1583
Nicolò De PretisGastroenterology and Digestive Endoscopy Unit, University Hospital of Verona, 37134 Verona, Italy.
Luca FrulloniGastroenterology and Digestive Endoscopy Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0001-7417-2655
Stefano Francesco CrinòGastroenterology and Digestive Endoscopy Unit, University Hospital of Verona, 37134 Verona, Italy.ORCID 0000-0003-4560-8741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cystic lesions (PCLs) pose a diagnostic challenge due to their increasing incidence and the limitations of cross-sectional imaging and endoscopic-ultrasound-guided fine-needle aspiration (EUS-FNA). EUS-guided through the needle biopsy (EUS-TTNB) has emerged as a promising tool for improving the accuracy of cyst type determination and neoplastic risk stratification. EUS-TTNB demonstrates superior diagnostic performance over EUS-FNA, providing critical preoperative information that can significantly influence patient management and reduce unnecessary surgeries. However, the procedure has risks, with an overall adverse event rate of approximately 9%. Preventive measures and further prospective studies are essential to optimize its safety and efficacy. This review highlights the potential of EUS-TTNB to enhance the diagnostic and management approaches for patients with PCLs. It examines the current state of EUS-TTNB, including available devices, indications, procedural techniques, specimen handling, diagnostic yield, clinical impact, and associated adverse events.

Indexed as

cystic fluid analysisEUS-FNAintraductal papillary mucinous neoplasm (IPMN)mucinous cystic neoplasmneuroendocrine tumorpancreatic cancer

Identifiers

PMID39125463
PMCPMC11311500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.