Evidence map›Paper›PMID 39125456›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Evaluation of the Accuracy of Estimated Endpoint Titer of NOVA View in Indirect Immunofluorescent Antinuclear Antibody Testing.

Hae Weon Cho, Soon-Ho Jeong, Jun Sung Hong, Dokyun Kim, Yongjung Park, Seok Hoon Jeong

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hae Weon ChoDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Soon-Ho JeongDepartment of Laboratory Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Jun Sung HongDepartment of Companion Animal Health and Science, Silla University, Busan 46958, Republic of Korea.ORCID 0000-0003-4280-6187
Dokyun KimDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-0348-5440
Yongjung ParkDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-5668-4120
Seok Hoon JeongDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-9290-897X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For antinuclear antibody (ANA) screening, the gold standard method is an indirect immunofluorescence assay (IIFA) using HEp-2 cells, and a serial dilution test is needed to determine the endpoint titer. We aimed to evaluate the accuracy of the estimated endpoint titer (eEPT) by the NOVA View system, by comparing it with the EPT by the serial dilution method (dEPT). The endpoint titers of a total of 1518 ANA positive cases with five major patterns including speckled, homogeneous, centromere, nucleolar, and nuclear dots patterns were determined using both the estimation function and the serial dilution method by the NOVA View system. A significant correlation between the light intensity unit (LIU) values and dEPTs was identified in all five patterns with high

Indexed as

antibodiesantinuclearantinuclear antibodyautomationfluorescent antibody techniqueindirectindirect immunofluorescence assaylaboratoryserial dilution endpoint titrationsingle-well titration

Identifiers

PMID39125456
PMCPMC11311674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.