Evidence map›Paper›PMID 39125434›Full record

ArticleNutrients2024

Presepsin in Human Milk Is Delivery Mode and Gender Dependent.

Ebe D'Adamo, Chiara Peila, Mariachiara Strozzi, Roberta Barolo, Antonio Maconi, Arianna Nanni, Valentina Botondi, Alessandra Coscia, Enrico Bertino, Francesca Gazzolo and 7 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ebe D'AdamoNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Chiara PeilaNeonatology Unit, Department of Public Health and Pediatrics, University of Turin, 10124 Torino, Italy.ORCID 0000-0002-0075-5353
Mariachiara StrozziDepartment of Pediatrics and Neonatology, Cardinal Massaia Hospital, 14100 Asti, Italy.
Roberta BaroloNeonatology Unit, Department of Public Health and Pediatrics, University of Turin, 10124 Torino, Italy.
Antonio MaconiDepartment of Maternal, Fetal and Neonatal Medicine, ASO SS Antonio, Biagio and C. Arrigo, 15121 Alessandria, Italy.ORCID 0000-0002-1904-7277
Arianna NanniNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Valentina BotondiNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Alessandra CosciaNeonatology Unit, Department of Public Health and Pediatrics, University of Turin, 10124 Torino, Italy.
Enrico BertinoNeonatology Unit, Department of Public Health and Pediatrics, University of Turin, 10124 Torino, Italy.
Francesca GazzoloDepartment of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Ali Saber AbdelhameedDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5910-2832
Mariangela ConteNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Simonetta PiconeNeonatal Intensive Care Unit, Policlinico Casilino, 00169 Rome, Italy.
Marianna D'AndreaNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Mauro LizziNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0003-3075-9758
Maria Teresa QuartaNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.
Diego GazzoloNeonatal Intensive Care Unit, "G. D'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0002-0643-2555

Funding

I COLORI DELLA VITA FOUNDATION and DANONE 3/2019King Saud University RSPD2024R750
6 · The paper itself

Abstract

Breast milk (BM) is a unique food due to its nutritional composition and anti-inflammatory characteristics. Evidence has emerged on the role of Presepsin (PSEP) as a reliable marker of early sepsis diagnosis. In the present study, we aimed to investigate the measurability of PSEP in BM according to different maturation stages (colostrum, C; transition, Tr; and mature milks, Mt) and corrected for delivery mode and gender. We conducted a multicenter prospective case-control study in women who had delivered 22 term (T) and 22 preterm (PT) infants. A total of 44 human milk samples were collected and stored at -80 °C. BM PSEP (pg/mL) levels were measured by using a rapid chemiluminescent enzyme immunoassay. PSEP was detected in all samples analyzed. Higher (

Indexed as

Lipopolysaccharide ReceptorsMilk, HumanPeptide FragmentsAdultBiomarkersCase-Control StudiesDelivery, ObstetricFemaleHumansInfant, NewbornInfant, PrematureMalePregnancyProspective StudiesSex FactorsBiomarkersLipopolysaccharide ReceptorsPeptide Fragmentspresepsin protein, humanbreastmilknewbornnutritionpresepsinpretermsCD14

Identifiers

PMID39125434
PMCPMC11313726

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.