Evidence map›Paper›PMID 39125375›Full record

ReviewNutrients2024

The Antidiabetic Potential of Probiotics: A Review.

Shiming Li, Zichao Liu, Qi Zhang, Dan Su, Pengjie Wang, Yixuan Li, Wenbiao Shi, Qian Zhang

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Nutrients · 2025
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Novel probioticFrontiers in microbiology · 2025
    Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiming LiDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Zichao LiuDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Qi ZhangDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Dan SuDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14850, USA.
Pengjie WangDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-9975-6737
Yixuan LiDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Wenbiao ShiDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-7724-9582
Qian ZhangDepartment of Nutrition and Health, China Agricultural University, Beijing 100193, China.

Funding

Beijing Natural Science Foundation No. 7244368Beijing Nova Program 20220484144Chinese Universities Scientific Fund 2024RC013National Natural Science Foundation of China Grant 82272566the 111 Project from the Education Ministry of China B18053
6 · The paper itself

Abstract

Diabetes has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals. Diabetes is associated with numerous complications, such as obesity; hyperglycemia; hypercholesterolemia; dyslipidemia; metabolic endotoxemia; intestinal barrier damage; insulin-secretion defects; increased oxidative stress; and low-grade, systemic, and chronic inflammation. Diabetes cannot be completely cured; therefore, current research has focused on developing various methods to control diabetes. A promising strategy is the use of probiotics for diabetes intervention. Probiotics are a class of live, non-toxic microorganisms that can colonize the human intestine and help improve the balance of intestinal microbiota. In this review, we summarize the current clinical studies on using probiotics to control diabetes in humans, along with mechanistic studies conducted in animal models. The primary mechanism by which probiotics regulate diabetes is improved intestinal barrier integrity, alleviated oxidative stress, enhanced immune response, increased short-chain fatty acid production, etc. Therefore, probiotic supplementation holds great potential for the prevention and management of diabetes.

Indexed as

Gastrointestinal MicrobiomeProbioticsAnimalsDiabetes MellitusDiabetes Mellitus, Type 2HumansOxidative Stressgut microbiotaprobioticsT2DM

Identifiers

PMID39125375
PMCPMC11313988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.