Evidence map›Paper›PMID 39125362›Full record

ArticleNutrients2024

Adherence to the Mediterranean Diet Mitigates Inflammation and Hospital Stay in Frail Elderly Patients: A Moderation Analysis.

Aurelio Lo Buglio, Francesco Bellanti, Rosanna Maria Carapellese, Cristiano Capurso, Gaetano Serviddio, Gianluigi Vendemiale

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aurelio Lo BuglioDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0003-1569-3658
Francesco BellantiDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-8196-7373
Rosanna Maria CarapelleseDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.
Cristiano CapursoDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-1152-3371
Gaetano ServiddioDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-6424-7841
Gianluigi VendemialeDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.

Funding

"HEAL ITALIA - Health Extended Alliance for Innovative Therapies, Advanced Lab-research and Integrated Approaches of Precision Medicine" Cod. PE_00000019 with finanzial contribution of European Union - NextGenerationUE as part of PNRR MUR - M4C2 - Investi Cod. PE_00000019
6 · The paper itself

Abstract

Understanding the interaction between dietary patterns and nutritional status in influencing health outcomes is crucial, especially in vulnerable populations. Our study investigates the impact of adherence to the Mediterranean diet (MD) and nutritional status on inflammatory markers (CRP) and the length of stay (LOS) in hospitalized frail elderly patients.

methodsWe conducted two-way ANOVA and multiple regression analysis to evaluate the effects of nutritional status and MD adherence on the CRP levels and LOS in a cohort of 117 frail elderly patients aged 65 years or older. Patients with cancer or acute infection were excluded. Adherence to the MD was assessed using the 14-item PREDIMED questionnaire.

resultsSignificant interactions were found between nutritional status and MD adherence for both the CRP and LOS. The patients with low-level MD adherence and a poor nutritional status exhibited higher CRP levels and longer hospital stays compared to those with high MD adherence. Specifically, a statistically significant interaction was observed for the CRP (

conclusionsThese findings highlight the importance of promoting the MD, particularly in malnourished elderly patients, to improve health outcomes and reduce hospitalization duration. Further longitudinal studies are warranted to establish causality and explore the underlying mechanisms.

Indexed as

C-Reactive ProteinDiet, MediterraneanFrail ElderlyInflammationLength of StayNutritional StatusAgedAged, 80 and overBiomarkersFemaleHospitalizationHumansMaleMalnutritionPatient ComplianceBiomarkersC-Reactive ProteinCRPelderly peoplefrailtyhospitalized elderly peopleinflammatory markerslength of staymalnutritionMediterranean dietnutritional status

Identifiers

PMID39125362
PMCPMC11314230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.