Evidence map›Paper›PMID 39125310›Full record

ArticleNutrients2024

The Role of Combined Muscle Ultrasound and Bioimpedentiometry Parameters for Sarcopenia Diagnosis in a Population of Hospitalized Older Adults.

Alfredo Zanotelli, Andrea P Rossi, Letizia Del Monte, Gianluca Vantini, Giovanni Stabile, Silvia Urbani, Anna Giani, Elena Zoico, Alessio Babbanini, Francesco Fantin and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alfredo ZanotelliSection of Geriatric Medicine, Ospedale Santa Maria del Carmine, 38068 Rovereto, Italy.
Andrea P RossiDivision of Geriatrics, Department of Medicine, Ospedale Cà Foncello, 31100 Treviso, Italy.ORCID 0000-0002-5472-1175
Letizia Del MonteDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.
Gianluca VantiniDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.
Giovanni StabileDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.ORCID 0000-0002-0858-2477
Silvia UrbaniDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.
Anna GianiDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.
Elena ZoicoDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.ORCID 0000-0002-5235-1545
Alessio BabbaniniDivision of Geriatrics, Department of Medicine, Dentistry, Pediatric and Gynecology, Healthy Aging Center, University of Verona, 37126 Verona, Italy.
Francesco FantinDivision of Geriatrics, University of Trento, 38100 Trento, Italy.ORCID 0000-0003-1763-6024
Mauro ZamboniDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.
Gloria MazzaliDepartment of Medicine, Geriatrics Division, University of Verona, 37100 Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor the study of quantitative and qualitative muscle parameters, ultrasound and bioelectric impedance analysis are reliable, non-invasive, and reproducible. The aim of this study was to test the combined role of those techniques for the diagnosis of sarcopenia in a population of hospitalized older males and females.

methodsA total of 70 subjects were recruited, including 10 healthy adults and 60 hospitalized elderly patients with a good level of independence and cooperation, with and without sarcopenia. The rectus femoris cross-sectional area (CSA), thickness, echogenicity, and compressibility were measured with ultrasound echography. The phase angles (PhAs) and skeletal muscle mass were calculated by bioimpedence analysis. The muscle quality index (MQI) was calculated as the product of CSA and PhA.

resultsMuscle compressibility was greater and PhA was lower in sarcopenic when compared with non-sarcopenic subjects. The threshold values for sarcopenia diagnosis in both sexes of CSA, of PhA, and of the MQI were identified. The obtained CSA values showed an AUC of 0.852 for women and 0.867 for men, PhA of 0.792 in women and 0.898 in men, while MQI was 0.900 for women and 0.969 for men.

conclusionsThe newly calculated cut-off values of CSA, PhA, and MQI predicted the presence of sarcopenia with good sensitivity and specificity values. The use of the MQI proved to be more promising than the separate use of CSA and PhA in both male and female subjects.

Indexed as

Electric ImpedanceMuscle, SkeletalSarcopeniaUltrasonographyAgedAged, 80 and overBody CompositionFemaleHospitalizationHumansMaleQuadriceps Musclebioimpedentiometrymusclemuscle qualitymuscle ultrasoundmyosteatosisphase anglesarcopenia

Identifiers

PMID39125310
PMCPMC11313821

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.