Evidence map›Paper›PMID 39125186›Full record

ArticlePolymers2024

In Vitro and Ex Vivo Evaluation of Novel Methacrylated Chitosan-PNIPAAm-Hyaluronic Acid Hydrogels Loaded with Progesterone for Applications in Vaginal Delivery.

Oana-Teodora Afloarea, Isabella Nacu, Liliana Vereștiuc, Cătălina Natalia Yilmaz, Alina Diana Panainte, Cătălina Anișoara Peptu, Iulia-Giorgiana Ostafe, Nela Bibire

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Oana-Teodora AfloareaDoctoral School, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700116 Iasi, Romania.
Isabella NacuFaculty of Medical Bioengineering, Department of Biomedical Sciences, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700116 Iasi, Romania.ORCID 0009-0005-5165-659X
Liliana VereștiucFaculty of Medical Bioengineering, Department of Biomedical Sciences, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700116 Iasi, Romania.ORCID 0000-0002-3098-8406
Cătălina Natalia YilmazFaculty of Science, Department of Chemistry, Biochemistry Division, Dokuz Eylül University, Kültür Mah. Cumhuriyet Bulv. No:144 Alsancak, 35210 Izmir, Turkey.ORCID 0000-0001-5229-8986
Alina Diana PanainteFaculty of Pharmacy, Department of Analytical Chemistry, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700116 Iasi, Romania.
Cătălina Anișoara PeptuFaculty of Chemical Engineering and Environmental Protection "Cristofor Simionescu", Department of Natural and Synthetic Polymers, "Gheorghe Asachi" Technical University of Iasi, 700050 Iasi, Romania.
Iulia-Giorgiana Ostafe"Cuza Voda" Obstetrics and Gynecology Clinical Hospital, 34 Cuza Voda Street, 700038 Iasi, Romania.
Nela BibireFaculty of Pharmacy, Department of Analytical Chemistry, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700116 Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Miscarriage is defined as the loss of a pregnancy before 24 weeks and administration of progesterone in pregnancy has considerably decreased the risk of premature birth. Progesterone (PGT) starting from the luteal phase stabilizes pregnancy, promotes differentiation of the endometrium, and facilitates the implantation of the embryo. Within the present study, novel hybrid hydrogels based on chitosan methacrylate (CHT), hyaluronic acid (HA), and poly(

Indexed as

chitosan methacrylatehyaluronic acidmucoadhesionNIPAAmprogesteronevaginal tissue

Identifiers

PMID39125186
PMCPMC11313938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.