Evidence map›Paper›PMID 39124908›Full record

ArticleMolecules (Basel, Switzerland)2024

Investigation of the Anti-Inflammatory Properties of Bioactive Compounds from

Tom C Karagiannis, Katherine Ververis, Julia J Liang, Eleni Pitsillou, Evan A Kagarakis, Debbie T Z Yi, Vivian Xu, Andrew Hung, Assam El-Osta

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tom C KaragiannisEpigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3004, Australia.ORCID 0000-0002-9967-1546
Katherine VerverisEpigenomic Medicine Laboratory at prospED Polytechnic, Carlton, VIC 3053, Australia.
Julia J LiangEpigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3004, Australia.ORCID 0000-0002-3031-3169
Eleni PitsillouEpigenomic Medicine Laboratory at prospED Polytechnic, Carlton, VIC 3053, Australia.
Evan A KagarakisEpigenomic Medicine Laboratory at prospED Polytechnic, Carlton, VIC 3053, Australia.
Debbie T Z YiEpigenomic Medicine Laboratory at prospED Polytechnic, Carlton, VIC 3053, Australia.
Vivian XuEpigenomic Medicine Laboratory at prospED Polytechnic, Carlton, VIC 3053, Australia.
Andrew HungSchool of Science, STEM College, RMIT University, Melbourne, VIC 3001, Australia.ORCID 0000-0003-3569-2951
Assam El-OstaEpigenetics in Human Health and Disease Program, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3004, Australia.ORCID 0000-0001-7968-7375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a landmark study, oleocanthal (OLC), a major phenolic in extra virgin olive oil (EVOO), was found to possess anti-inflammatory activity similar to ibuprofen, involving inhibition of cyclooxygenase (COX) enzymes. EVOO is a rich source of bioactive compounds including fatty acids and phenolics; however, the biological activities of only a small subset of compounds associated with

Indexed as

Anti-Inflammatory AgentsCyclooxygenase InhibitorsMolecular Docking SimulationOleaAldehydesArachidonate 15-LipoxygenaseComputer SimulationCyclooxygenase 1Cyclooxygenase 2Cyclopentane MonoterpenesHumansMolecular Dynamics SimulationOlive OilPhenolsPhytochemicalsPlant ExtractsAldehydesAnti-Inflammatory AgentsArachidonate 15-LipoxygenaseCyclooxygenase 1Cyclooxygenase 2Cyclooxygenase InhibitorsCyclopentane MonoterpenesoleocanthalOlive OilPhenolsPhytochemicalsPlant ExtractsProstaglandin-Endoperoxide Synthasesanti-inflammatorycyclooxygenase enzymesOlea europaeaoleocanthaloleohydroxypyretololive phenolics

Identifiers

PMID39124908
PMCPMC11314539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.