ArticleMaterials (Basel, Switzerland)2024
Composite Nanoarchitectonics of Electrospun Piezoelectric PVDF/AgNPs for Biomedical Applications, Including Breast Cancer Treatment.
Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Enhancement of the piezoelectric response of corona charged Ag/P(VDF-TrFE) nanocomposites for energy harvesting devices.Scientific reports · 2026Article
- Fascinating Frontier, Nanoarchitectonics, as Method for Everything in Materials Science.Materials (Basel, Switzerland) · 2025Review
- Biopiezoelectric-based nanomaterials; a promising strategy in cancer therapy.Journal of experimental & clinical cancer research : CR · 2025Review
- Experimental and Numerical Characterization of Electrospun Piezoelectric Polyvinylidene Fluoride Nanocomposites Reinforced with Silver Nanoparticles.Materials (Basel, Switzerland) · 2025Article
- Piezoelectric Nanomaterials for Cancer Therapy: Current Research and Future Perspectives on Glioblastoma.Journal of functional biomaterials · 2025Review
- Layer-by-Layer Nanoarchitectonics: A Method for Everything in Layered Structures.Materials (Basel, Switzerland) · 2025Review
- Materials Nanoarchitectonics for Advanced Devices.Materials (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
5 authors.
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Abstract
This study focused on preparing composite nanomats by incorporating silver nanoparticles (AgNPs) in polyvinylidene fluoride (PVDF) nanofibers through the electrospinning process. A short review of piezoelectric PVDF-related research is presented. PVDF is known for its biocompatibility and piezoelectric properties. Since electrical signals in biological tissues have been shown to be relevant for therapeutic applications, the influence of the addition of AgNPs to PVDF on its piezoelectricity is studied, due to the ability of AgNPs to increase the piezoelectric signal, along with providing antibacterial properties. The prepared samples were characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and Fourier transform infrared spectroscopy. In addition, the biological activity of composites was examined using a cytotoxicity assay and an assessment of the antibacterial activity. The obtained results show that the incorporation of AgNPs into PVDF nanofibers further enhances the piezoelectricity (crystalline β-phase fraction), already improved by the electrospinning process, compared to solution-casted samples, but only with a AgNPs/PVDF concentration of up to 0.3%; a further increase in the nanoparticles led to a β-phase reduction. The cytotoxicity assay showed a promising effect of PVDF/AgNPs nanofibers on the MDA-MB-231 breast cancer cell line, following the non-toxicity displayed in regard to the healthy MRC-5 cell line. The antibacterial effect of PVDF/AgNPs nanofibers showed promising antibacterial activity against
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Registered trials
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